{"id":379,"date":"2012-05-31T16:11:30","date_gmt":"2012-05-31T07:11:30","guid":{"rendered":"http:\/\/p.bunri-u.ac.jp\/english\/?p=379"},"modified":"2022-07-02T12:57:41","modified_gmt":"2022-07-02T03:57:41","slug":"medicinal-chemistry-tsunoda-lab","status":"publish","type":"post","link":"https:\/\/p.bunri-u.ac.jp\/english\/379\/","title":{"rendered":"Medicinal Chemistry (Kaku Lab.)"},"content":{"rendered":"

Staff<\/span>
\nProf. Dr. Hiroto Kaku
\nDr. Kei Kitamura<\/h2>\n

Research project<\/span><\/p>\n

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Publications<\/span><\/p>\n

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  1. Strong acid-promoted skeletal remodeling of the aphid pigment: red uroleuconaphin to green viridaphin<\/b>, Chiharu Ozakai, Kei Kitamura, Mitsuyo Horikawa, To-sho Hoshiyama, Akari Imamura, Tatsuro Yoneyama, Akemi Umeyama, Masaaki Noji, Tetsuto Tsunoda, Hiroto Kaku, New J. Chem.<\/i>, 2022<\/b>, 46, 2600-2604. DOI:10.1039\/D1NJ05261F<\/a><\/li>\n
  2. Synthesis of the Common Monomeric Unit of Uroleuconaphins and Viridaphins via Hauser\u2013Kraus Annulation<\/b>,
    \nKei Kitamura, Hinano Kanagawa, Chiharu Ozakai, Taichi Nishimura, Hayato Tokuda, Tetsuto Tsunoda, Hiroto Kaku, SYNTHESIS<\/i>, 2021<\/b>, 53 (9), 1629-1635. DOI:    10.1055\/a-1334-6982<\/a><\/li>\n
  3. Total Syntheses and Cytotoxic Evaluations of Cryptolactones A1, A2, B1, B2, and Their Derivatives<\/b>, Makoto Inai, Yoki Oguri, Mitsuyo Horikawa, Hiroto Kaku, Shinya Suzuki, Kei Kitamura, Tetsuto Tsunoda, Chem. Pharm. Bull.<\/i>, 2020<\/b>, 68 (4), 380-383. DOI:10.1248\/cpb.c19-01114<\/a><\/li>\n
  4. Piperidine and Azetidine Formation by Direct Cyclization of Diols with N-Nonsubstituted Sulfonamide under the Mitsunobu Conditions Utilizing (Cyanomethylene)tributylphosphorane (CMBP) and Its Application to the Synthesis of Lupinine<\/b>, Hiroto Kaku, Yuhei Sonoda, Hideyuki Hishida, Yuri Taniguchi, Akiko Kubo, Takumi Hamaguchi, Mitsuyo Horikawa, Makoto Inai, Kei Kitamura, Tetsuto Tsunoda, HETEROCYCLES<\/i>, 2019<\/b>, 98 (11), 1525-1535. DOI:10.3987\/COM-19-14171<\/a><\/li>\n
  5. Optically Active 2,7,10,15-Tetrahydroxytetraphenylene: Clathrates with Both Enantiomers of 1-Phenylethylamine and Their Stability<\/b>, Hiroto Kaku, Akinobu Mitarai, Natsuko Okamoto, Kenta Tanaka, Sayaka Ichikawa, Takahiro Yamamoto, Makoto Inai, Takeshi Nishii, Mitsuyo Horikawa, Tetsuto Tsunoda, Eur. J. Org. Chem.<\/i>, 2018<\/b>, 48, 6991-6999. DOI:ejoc.201801422<\/a><\/li>\n
  6. A role of uroleuconaphins, polyketide red pigments in aphid, as a chemopreventor in the host defense system against infection with entomopathogenic fungi<\/b>, Mitsuyo Horikawa, Mitsuaki Shimazu, Maki Aibe, Hiroto Kaku, Makoto Inai, Tetsuto Tsunoda, J. Antibiotics<\/i>, 2018<\/b>, 71, 992\u2013999. DOI:10.1038\/s41429-018-0093-4<\/a><\/li>\n
  7. 3,3-Dimethoxypropylsulfonyl Group: A new versatile protecting and activating group for amine synthesis<\/b>, Izumi Sakamoto, Kazuya Iwaoka, Yuta Kawada, Takanori Naito, Kazuyoshi Makida, Yuki Takeuchi, Takeshi Nishii, Mitsuyo Horikawa, Hiroto Kaku, Tetsuto Tsunoda, Tetrahedron<\/i>, 2018<\/b>, 74 (24), 3052-3060. DOI:10.1016\/j.tet.2018.04.088<\/a><\/li>\n
  8. Deracemization of \u03b1-monosubstituted cyclopentanones in the presence of a TADDOL-type host molecule<\/b>, >Hiroto Kaku, Minami Ito, Mitsuyo Horikawa, Tetsuto Tsunoda, Tetrahedron<\/i>, 2018<\/b>, 74 (4), 124-129. DOI:10.1016\/j.tet.2017.11.045<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Staff Prof. Dr. Hiroto Kaku Dr. Kei Kitamura Research project Publications Strong acid-promoted skeletal … \u7d9a\u304d\u3092\u8aad\u3080 Medicinal Chemistry (Kaku Lab.)<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[34],"tags":[],"_links":{"self":[{"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/posts\/379"}],"collection":[{"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/comments?post=379"}],"version-history":[{"count":30,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/posts\/379\/revisions"}],"predecessor-version":[{"id":1005,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/posts\/379\/revisions\/1005"}],"wp:attachment":[{"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/media?parent=379"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/categories?post=379"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/p.bunri-u.ac.jp\/english\/wp-json\/wp\/v2\/tags?post=379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}