Publication

       

2020

  • Elshamy, A., I., Mohamed, A., T., Swapana, N., Yoneyama, T.,Noji, M., Efferth, T., ,Hegazy., ME., F., Umeyama, A., "Cytotoxic polyoxygenated isopimarane diterpenoids from the edible rhizomes of Kaempferia galanga (kencue)" Ind. Crops Prod. 2020, 158, 112965. DOI: org/10.1016/j.indcrop.2020.112965
  • Elshamy, A., I.,Aty, A., A., Yoneyama, T., Hussien, T., A., Imagwa, H., Suenaga, M., Umeyama, A., Hegazy., T., A., "New isopimaradiene from keampulchraol E via Rhizopus oryzae fungal transformation" Phytochem. Lett. 2020, 38, 107-111.DOI: .org/10.1016/j.phytol.2020.05.006
  • Yoneyama, T., Iseki, K., Baba, C., Kitagawa Y., Yoshikawa, K., Kawano, S., Ishiyama, A., Hokari, R., Iwatsuki, M., Otoguro, K., Ōmura, S., Hashimoto, T., Noji, M., Umeyama, A., "Phenanthrenes with Potent Antitrypanosomal Activity from Roots of Cymbidium Great Flower 'Marylaurencin'" Shouyakugaku Zasshi 2020, 74(2), 106-107.

  • Elshamy, A., I., Yoneyama, T., Trang, N., V., Son, N., T., Okamoto, Y., Noji, M., Ban, S., Umeyama, A. “A new cerebroside from the entomopathogenic fungus Ophiocordyceps longiissima: Structural-electronic and antioxidant relations. Experimental and DFT calculated studies” Journal of Molecular structure 2020, 1200, 127061. DOI: 10.1016/j.molstruc.2019.127061

2019

  • Hammami, S., Elshamy, A., I., Mokni, R., E., Snene, A., Iseki, K., Dhaouadi, H., Okamoto, Y., Suenaga, M., Noji, M., Umeyama, A., Asakawa, Y., “Chemical Constituents of the Aerial Parts of Daucus carota subsp. hispidus Growing in Tunisia” Nat. Prod. Comm., 2019, 1-6. DOI: .org/10.1177/1934578X19863512

  • Elshamy, A., I., Mohamed, T., A., Suenaga, M., Noji M., Umeyama., A., Efferth, T., Hegazy, M. F., “New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata” Phytochem. Lett., 2019, 34, 74-78. DOI: .org/10.1016/j.phytol.2019.09.016

  • Elshamy, A., I., Mohamed, T., A., Essa, A., F., Abd-ElGawad, A., M., Alqahtani, A., S., Shahat, A., A., Yoneyama, T., Farrag., A., R., H., Noji, M., El-Seedi, H., R., Umeyama, A., Paré., P., W., Hegazy, M., F., “Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review” nutrients, 2019, 11, 2396. DOI: .org/10.3390/nu11102396

  • Hama, M.,Elshamy A., I., Yoneyama, T., Kasai, Y., Yamamoto, H., Tanigawa, K., Oshiro, A., Noji, M., Ban, S., Imagawa, H., Umeyama, A., “New alkaloidal metabolites from cultures of entomopathogenic fungus Cordyceps takaomontana NBRC 101754” ” Fitoterapia, 2019, 139, 104364. DOI: .org/10.1016/j.fitote.2019.104364
  • Yoneyama, T., Iseki, K., Noji, M., Imagawa, H., Hashimoto, T., Kawano, S., Baba, M., Kashiwada, Y., Yahagi, T., Matsuzaki, K., Umeyama, A. “Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’” Molecules 2019, 24(13), 2504. DOI: 10.3390/molecules24132504

2018

  • Swapana, N., Tominaga, T., Suenaga, M., Imagawa, H., Noji, M., Elshamy, A., I., Ibrahim, M., A., A., Hegazy, M., F., Brajakishor, S., C., Umeyama, A. “Kaemgalangol A: Unusual seco-​isopimarane diterpenoid from aromatic ginger Kaempferia galanga” Fitoterapia 2018, 129, 47-53. DOI: 10.1016/j.fitote.2018.06.010
  • Kukula-Koch, W., Koch, W., Czernicka, L., Głowniak, K., Asakawa, Y., Umeyama, A., Marzec,Z., Kuzuhara, T. “MAO-​A Inhibitory Potential of Terpene Constituents from Ginger Rhizomes-​A Bioactivity Guided Fractionation” Molecules 2018, 23(6). DOI: 10.3390/molecules23061301
  • Elshamy, A., I., Mohamed, T., A., Marzouk, M., M., Hussien, T., A., Umeyama, A., Hegazy, M., E., F., Efferth, T. “Phytochemical constituents and chemosystematic significance of Pulicaria jaubertii E.Gamal-​Eldin (Asteraceae) ” Phytochemistry Letters 2018, 24, 105-109.  DOI: 10.1016/j.phytol.2018.01.021
2017
  • Raslan, M. A., Melekb, F. R., Said, A., A., Elshamy, A., I., Umeyama, A., Mounier, M., M. “New cytotoxic dihydrochalcone and steroidal saponins from the aerial parts of Sansevieria cylindrica Bojer ex Hook” Phytochemistry Letters 2017, 22, 39-43. DOI: 10.1016/j.phytol.2017.0

  • Elshamy, A., I., El-Shazly, M., Yassine, Y., M., El-Bana, M., A., Farrag, A., Nassar, M., I., Noji, M., Umeyama, A. “Phenolic constituents, anti-inflammatory and antidiabetic activities of Cyperus laevigatus L” Pharmacognosy J. 2017, 448, 828-833. DOI:10.5530/pj.2017.6.129

  • El-kashak, W., A, Elshamy, A., I., Mohamed, T., A., El Gendy, A.G., Saleh, I., A., Umeyama, A. “Rumpictuside A: Unssual 9,10-anthraquionone glucoside from Rumex pictus Forssk” Carbohydrate Research 2017, 448, 74-78. DOI: 10.1016/j.carres.2017.05.023
  • Swapana, N., Noji, M., Nishiuma, R., Izumi, H., Imagawa, H., Kasai, Y., Okamoto, Y., Iseki, K., Singh, Ch., B., Asakawa, Y., Umeyama, A. “A new diphenyl ether glycoside from Xylosma longifolium collected from north-east India” Nat. Prod. Commun. 2017, 12, 1273-1275.
  • Kokudo, N., Okazoe, M., Takahashi, J., Iseki, K., Yoshikawa, K., Imagawa, H., Hashimoto, T., Noji, M., Umeyama, A. “Six new lanostane triterpenoids from the fruiting body of Tyromyces sambuceus and antiproliferative activity.” Nat. Prod. Commun., 2017, 11, 169-172.

2016

  • Nishio, A., Mikami, H., Imagawa, H., Hashimoto, T., Tanaka, M., Ito, T., Iguchi, M., Iseki, K., Noji, M., Umeyama, A. “Two novel diphenolic metabolites from the inedible mushroom Thelephora palmate”Nat. Prod. Commun., 2016, 11, 1147-1149. 
  • Ganaha, M., Yoshii, K., Ōtsuki, Y., Iguchi, M., Okamoto, Y., Iseki, K., Ban, S., Ishiyama, A., Hokari, R., Iwatsuki, M., Otoguro, K., Ōmura, S., Hashimoto, T., Noji, M., Umeyama, A. “In vitro antitrypanosomal activity of the secondary metabolites from the mutant strain IU-3 of the insect pathogenic fungus Ophiocordyceps coccidiicola NBRC100683” Chem. Pharm. Bull., 2016, 64, 988–990. DOI: 10.1248/cpb.c16-00220
2014  
  • Umeyama, A., Ohta, C., Shino, Y., Okada M., Nakamura Y., Hamagaki T., Imagawa H., Suenaga M., Tanaka M., Ishiyama A., Iwatsuki, K., Otoguro M., Ōmura S., Hashimoto T. “Three lanostane triterpenoids with antitrypanosomal activity from the fruiting body of Hexagonia tenuis.” Tetrahedron 2014, 70(44), 8312-8315. DOI: 10.1016/j.tet.2014.09.013
  • Grudniewska, A., Hayashi, S., Shimizu, M., Kato, M., Suenaga, M., Imagawa, H., Ito, T., Asakawa, Y., Ban, S., Kumada, T., Hashimoto, T., Umeyama, A. “Opaliferin, a New Polyketide from Cultures of Entomopathogenic Fungus Cordyceps sp. NBRC 106954” Organic Letters, 2014, 16 (18), 4695–4697. DOI: 10.1021/ol502216j
  • Umeyama, A., Takahashi, K., Grudniewska, A., Shimizu, M., Hayashi, S., Kato, M., Okamoto, Y., Suenaga, M., Ban S., Kumada, T., Ishiyama, A., Iwatsuki, M., Otoguro, K., Ōmura, S., Hashimoto, T. “In vitro antitrypanosomal activity of the cyclodepsipeptides, cardinalisamides A–C, from the insect pathogenic fungus Cordyceps cardinalis NBRC 103832” The Journal of Antibiotics 2014, 67, 163-167. DOI: 10.1038/ja.2013.93 

2013 

  • Kim,  K., S., Umeyama A., Hashimoto T., Cho H.- J., Lee J.- J., Takei M. “Effect of Farnesyl Caffeate-Induced Apoptosis of Lung Carcinoma Cell Line from Damage to DNA“ Pharmacology & Pharmacy, 2013, 4(9), 689-695. DOI: 10.4236/pp.2013.49096

2012

  • Takei, M., Umeyama, A., Lee J. -J. “The potential use of triterpene compounds in dendritic cells-based immunotherapy” Advancements in Tumor Immunotherapy and Cancer Vaccines 2012, 141-154. DOI: 10.5772/28764

2011

  • Kim K., S., Pham, T., N., N., Jin C.- J., Umeyama A., Shoji, N., Hashimoto T., Lee J.- J., Takei M. “Uncarinic acid C isolated from Uncaria rhynchophylla induces differentiation of Th1-promoting dendritic cells through TLR4 signaling” Biomarker Insights, 2011, 6, 27-38. DOI: 10.4137/BMI.S6441
  • Takei, M., Umeyama, A., Lee, J.- J. “The Possible Use of Terpene Compounds in DC Immunotherapy against Cancer” Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2011, 4(1), 69-74. DOI : 10.2174/187221410790226783

2010

  • Bae, W., K., Umeyama, A., Chung, I.- J., Lee J.- J., Takei, M. “Uncarinic acid C plus IFN-γ generates monocyte-derived dendritic cells and induces a potent Th1 polarization with capacity to migrate” Cellular Immunology, 2010, 266(1), 104-110. DOI: 10.1016/j.cellimm.2010.09.004
  • Umeyama, A., Yahisa, Y., Okada, M., Okayama E., Uda A., Shoji N., Lee J. -J., Takei, M., Hashimoto, T. “Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization” J. Nat. Med. 2010 64(4), 506-509. DOI 10.1007/s11418-010-0438-1
  •  Jung, T.- Y., Pham, T., N., N., Umeyama, A., Shoji, N., Hashimoto, T., Lee, J.- J., Takei, M. “Ursolic acid isolated from Uncaria rhynchophylla activates human dendritic cells via TLR2 and/or TLR4 and induces the production of IFN-γ by CD4+ naive T cells” European Journal of Pharmacology 2010, 643(2-3), 297-303. DOI: 10.1016/j.ejphar.2010.06.030
  • Takei, M., Umeyama, A., Shoji N., Hashimoto, T. “44.  Polyacetylenediols regulate the function of human monocyte -derived dendritic cells” International Immunopharmacology 2010, 10(8), 913-921. DOI: 10.1016/j.intimp.2010.05.002   
  • Takei, M., Umeyama, A., Lee, J.- J., Shoji, N., Hashimoto, T. “Cryptomerione induces Th1 cell polarization via influencing IL-10 production by cholera toxin-primed dendritic cells” European Journal of Pharmacology, 2010, 628, (1-3), 233-239. DOI: 10.1016/j.ejphar.2009.11.031
  • Umeyama, A., Matsuoka, N., Mine, R., Nakata, A., Arimoto, E., Matsui, M., Shoji, N., Arihara, S., Takei, M., Hashimoto, T. “Polyacetylene diols with antiproliferative and driving Th1 polarization effects from the marine sponge Callyspongia sp.” J. Nat. Med., 2010, 64(1), 93-97. DOI: 10.1007/s11418-009-0363-3 

2008

  • Takei, M., Umeyama, A., Shoji, N., Hashimoto, T. “Diterpenes drive Th1 polarization depending on IL-12” International Immunopharmacology, 2008, 8(11), 1602-1608. DOI: 10.1016/j.intimp.2008.07.003
  • Takei, M., Umeyama, A., Shoji, N., Hashimoto, T. “Differential Regulation of DC Function by Siphonodiol” Immunopharmacology and Immunotoxicology, 2008, 30(2), 425-435. DOI: 10.1080/08923970801949257
  • 橋本敏弘, 吉川和子, 梅山明美, 浅川義範 “きのこ類より生活習慣病予防薬および抗耐性菌薬の探索研究” 日本菌学会西日本支部会報, 2008, 17, 19-26.
  • Takei, M., Tachikawa, E., Umeyama, A., “Dendritic cells promoted by ginseng saponins drive a potent Th1 polarization” Biomarker Insights, 2008, 3, 269-286. DOI: 10.4137/BMI.S585
  • Takei, M., Umeyama, A., Shoji, N., Hashimoto, T. “Diterpene, 16-phyllocladanol enhances Th1 polarization induced by LPS-primed DC, but not TNF-α -primed DC.” Biochemical and Biophysical Research Communications, 2008, 370(1), 6-10.  DOI: 10.1016/j.bbrc.2008.02.157

2007 

  • 橋本敏弘, , 国土直樹, 矢野華恵, 吉川和子, 梅山明美, 在原重信 “地衣類イワタケおよびハナゴケより得られる新規生理活性物質” Lichenology, 2007, 6(2), 168.
  • Takei, M., Umeyama, A., Arihara, S. “Diterpenes inhibit IL-12 production by DC and enhance Th2 cells polarization” Biochemical and Biophysical Research Communications 2007, 355(3), 603-610. DOI: 10.1016/j.bbrc.2007.01.157

2006

  • Yoshikawa, K., Suzuki, K., Umeyama, A., Arihara, S. “Abietane diterpenoids from the barks of Cryptomeria japonica” Chem. Pharm. Bull., 2006, 54(4), 574-578. DOI: 10.1248/cpb.54.574

  • Takei, M., Umeyama, A., Arihara, S. “T-cadinol and calamenene induce dendritic cells from human monocytes and drive Th1 polarization” European Journal of Pharmacology, 2006, 537(1-3), 190-199. DOI: 10.1016/j.ejphar.2006.02.047 
  • Yoshikawa, K., Tanaka, T., Umeyama, A., Arihara, S. “Three abietane diterpenes and two diterpenes incorporated sesquiterpenes from the bark of Cryptomeria japonica” Chem. Pharm. Bull. 2006 54(3), 315-319. DOI: 10.1248/cpb.54.315

2005

  • Yoshikawa, K., Kouso, K., Takahashi, J., Matsuda, A., Okazoe, M., Umeyama, A., Arihara, S. “Cytotoxic Constituents of the Fruit Body of Daedalea dickisii” J. Nat. Prod., 2005, 68(6), 911-914. DOI: 10.1021/np058024c
  • Takei, M., Umeyama, A., Arihara, S. “Epicubenol and Ferruginol induce DC from human monocytes and differentiate IL-10-producing regulatory T cells in vitro” Biochemical and Biophysical Research Communications, 2005, 337(2), 730-738. DOI: 10.1016/j.bbrc.2005.09.110
  • Takei, M., Umeyama, A., Arihara, S. “Effect of Piceatannol in Human Monocyte-derived Dendritic Cells in Vitro” J. Pharm Sci., 2005, 94(5), 974-982. DOI: 10.1002/jps.20279 

2004

  • Arihara. S., Umeyama, A., Bandou, S., Kobuke, S., Imoto, S., Ono, M., Yoshikawa, K., Amita, K., Hasimoto, S. “Termiticidal Constituents of the Black-heart of Cryptomeria japonica” 木材学会誌, 2004, 50(6), 413-421. ISSN:0021-4795
  • Arihara, S., Umeyama, A., Bandou, S., Imoto, S., Ono, M., Yoshikawa, K. “Three New Sesquiterpenes from the Black Heartwood of Cryptomeria japonica” Chem. Pharm. Bull., 2004, 52 (4), 463-465. DOI: 10.1248/cpb.52.463
  • Arihara, S., Umeyama, A., Bandou, S., Imoto, S., Ono, M., Tani, M., Yoshikawa, K. “A New Abietane and Two Dimeric Abietane Diterpenes from the Black Heartwood of Cryptomeria japonica” Chem. Pharm. Bull., 2004, 52(3), 354-358. DOI: 10.1248/cpb.52.354

2000

  • Umeyama, A., Ito, S., Yoshigaki, A., Arihara, S. “Two New 26, 27-Cyclosterols from the Marine Sponge Strongylophora corticata” J. Nat. Prod. 2000 63(11), 1540-1542. DOI: 10.1021/np0002738
  • Umeyama, A., Adachi, K., Ito, S., Arihara, S. “New 24-Isopropylchole- sterol and 24-Isopropenyl cholesterol Sulfate from the Marine Sponge Epipolasis sp.” J. Nat. Prod. 2000, 63(8), 1175-1177. DOI: 10.1021/np000024j 

1998

  • Umeyama, A., Machida, M., Nozaki, M., Arihara, S. “Peroxypolasol and Mugipolasol: Two Novel Diterpenes from the Marine Sponge Epipolasis sp.” J. Nat. Prod. 1998 61(11), 1435-1436. DOI: 10.1021/np980210d
  • Umeyama, A., Ito, S., Yuasa, E., Arihara, S., Yamada, T. “A New Bromopyrrole Alkaloid and the Optical Resolutiom of Racemate from the Marine Sponge Homaxinella sp.” J. Nat. Prod. 1998, 61(11), 1433-1434. DOI: 10.1021/np980207u
  • Umeyama, A, Nozaki, M., Arihara, S. “Polasols A-C, Three New Diterpenes from the Marine Sponge Epipolasis sp.” J. Nat. Prod., 1998, 61(7), 945-947. DOI: 10.1021/np9705625 
  • Umeyama, A., Shoji, N., Enoki, M., Arihara, S. “Swinhosterols A-C, 4-Methylene Secosteroids from the Marine Sponge Theonella swinhoei”, J. Nat. Prod., 1997, 60(3), 296-298. DOI: 10.1021/np9606916 

1997

  • Umeyama, A., Nagano, C., Arihara, S. “Three Novevl C21 Polyacetylenes from the Marine Sponge Callyspongia sp.” J. Nat. Prod., 1997, 60(2), 131-133. DOI: 10.1021/np960682x 

1996

  • Umeyama, A., Shoji. N., Ozeki, M., Arihara, S. “Sarcoaldesterol A and B, Two New Polyhydroxylated Sterols from the Soft Coral Sarcophyton sp.” J. Nat. Prod. 1996, 59(9), 894-895. DOI: 10.1021/np960255j
  • Shoji, N., Umeyama, A., Teranaka, M., Arihara, S. “Four Novel Diterpenoids, Including Nakamurol A with a Unique Thelepogane Skeleton, from the Marine Sponge Agelas nakamurai” J. Nat. Prod. 1996, 59(4), 448-450. DOI: 10.1021/np960110c

1995

  • Takei, M., Umeyama, A., Shoji, N., Arihara, S., Endo, K. “Mechanism of Inhibition of IgE-Dependent Histamine Release from Rat Mast Cells by Penasterol and Penasterone” J. Pharm Sci. 1995, 84(2), 228-230. DOI: 10.1002/jps.2600840222
  • Kobayashi, J., Shinonaga, H., Shigemori, H., Umeyama, A., Shoji, N., Arihara, S. “Xestobergsterol C, A New Pentacyclic Steroid from the Okinawan Marine Sponge Ircinia sp. and Absolute Stereochemistry of Xestobergsterol A” J. Nat. Prod. 1995, 58(2), 312-318. DOI: 10.1021/np50116a029 

1994

  • Shoji, N., Umeyama, A., Yoshikawa, K., Nagai, M., Arihara, S. “Baccharane Glycosides from Seeds of Impatiens balsamina” Phytochemistry 1994, 37(5), 1437-1441. DOI: 10.1016/S0031-9422(00)90428-X
  • Shoji, N., Umeyama, A., Yoshikawa, K., Arihara, S. “Triterpenoid Glycosides from Anagallis arvensis” Phytochemistry1994, 37(5), 1397-1402. DOI: 10.1016/S0031-9422(00)90419-9 
  • Shoji, N., Umeyama, A., Takei, M., Arihara, S. “Potent Inhibitors of Histamine Release: Polyhydroxylated Sterols from the Okinawan Soft Coral Sinularia abrupta” J. Pharm Sci. 1994, 83(5), 761-762. DOI: 10.1002/jps.2600830534
  • Shoji, N., Umeyama, A., Yoshikawa, K., Arihara, S. “Structures of Anagallosaponins I-V and Their Companion Substances from Anagallis arvensi L” Chem. Pharm. Bull. 1994, 42(9), 1750-1755. DOI: 10.1248/cpb.42.1750 
  • Shoji, N., Umeyama, A., Saitou, N., Yoshikawa, K., Arihara, S. “Hosenkosides F, G, H, I, J and K, Novel Baccharane Glycosides from the Seeds of Impatiens balsamina” Chem. Pharm. Bull. 1994, 42(7), 1422-1426. DOI: 10.1248/cpb.42.1422
  • Shoji, N., Umeyama, A., Saitou, N., Yoshikawa, K., Kan, Y., Arihara, S. “Hosenkosides A, B, C, D and E, Novel Baccharane Glycosides from the Seeds of Impatiens balsamina” Tetrahedron, 1994, 50(17), 4973-4986. DOI: 10.1016/S0040-4020(01)90409-0

1993

  • Takei, M., Endo, K., Umeyama, A., Shoji, N. “Histamine release from rat mast cells induced by the inhibition of adenosinetriphosphatase for   sodium and potassium channels” J. Pharm. Sci. 1993, 82(1), 25-26. DOI: 10.1002/jps.2600820106
  • Shoji, N., Umeyama, A., Arihara, S. “A Novel Norditerpenoid from the Okinawan Soft Coral Sinularia sp.” J. Nat. Prod. 1993, 56(9), 1651-1653. DOI: 10.1021/np50099a035
  • Takei, M., Umeyama, A., Shoji, N., Arihara, S., Kobayashi, J., Endo, K. “Mechanism of Inhibition of IgE-dependent Histamine Releace from Rat Mast Cells by Xestobergsterol A from the Okinawan Marine Sponge Xestospongia bergquistia” Experientia, 1993, 49(2), 145-149. ISSN:0014-4754

1992

  • Shoji, N., Umeyama, A., Motoki, S., Arihara, S., Ishida, T., Nomoto, k., Kobayashi, J., Takei, M. “Potent Inhibitors of Histamine Release, Two Novel Triterpenoids from the Okinawan Marine Sponge Penares incrustans” J. Nat. Prod. 1992, 55(11), 1682-1685. DOI: 10.1021/np50089a021
  • Umeyama, A., Shoji, N., Takei Masao, Endo, K., Arihara, S. “Ciwujianoside D1 and C1: Powerful Inhibitors of　Histamine Release Induced by Anti- Immunoglobulin E from Rat Peritoneal Mast Cells” J. Pharm. Sci. 1992, 81(7) 661-662. DOI: 10.1002/jps.2600810714
  • Shoji. N., Umeyama, A., Sunahara, N., Arihara, S. “Ajureptoside, a Novel C9 Iridoid Glucoside from Ajuga reptans” J. Nat. Prod. 1992, 55(7), 1004-1006. DOI: 10.1021/np50085a030
  • Shoji, N., Umeyama, A., Shin, K., Takeda, K., Arihara, S., Kobayashi, J., Takei, M. “Two Unique Pentacyclic Steroids with Cis C/D Ring Junction from Xestospongia bergquistia Fromont, Powerful Inhibitors of Histamine Release” J. Org. Chem. 1992, 57(11), 2996-2997. DOI: 10.1021/jo00037a009
  • Shoji, N., Umeyama, A., Kishi, K., Arihara, S., Ohizumi, Y., Kobayashi, J. “Untenic Acid, a Novel Ca2+-ATPase Activator from Okinawan Marine Sponge” Aust. J. Chem. 1992, 45(4), 793-795. DOI: 10.1071/CH9920793