Prof. Tomoko Suzue
Research of our group is focused on the study of the adjsutment, assessment and establishment of drug usage and infomatic technology of drug interaction. Through studying, we expect to better understand the assessment of drug action for basic aspectd and clinical usage.
Basical assessment derived from the drug actions
-pharmacodynamics of drug-drug, drug-chemicals, drug-metal and drug-food
-action and mode of intracellular zinc-
-disorder of feeding and swallowing n the aging subjects and its disease-
-analysis of drug interaction using simple emulsion method-
Clinical assessment derived from the drug actions
-analysis of injectable surfactant on the cytotoxicity-
-propofol, an anesthetic possessing neuroprotective action against oxidative
stress, promotes the process of cells death induced by H2O2 in rat thymocytes-
-synergic cytotoxic action induced by simultaneous application of zinc and antifungals
-the interaction of zinc or these derivatives with oxidative stress-
-a new insight into toxicological characteristics of drug and supplement
Selected recent publications
- Hamada S, Morimoto M, Ohshima N, Shinohara Y, Suzue T, Ishida S. Usefulness in nasogastric tube blockage by addition of food thickener to suspension of Depakene® fine granules 40％. Jpn. J. Pharm. Health Care Sci. 47(11):616-22 (2021).
- Akiyama S, Arai K, Koshiishi T, Ishida S, Naomi Kurata. Survey on accumulated drug information by pharmaceutical companies about crushed or simply suspended internal medicines. Jpn. J. Drug Inform. 20(4):220-6 (2019).
- Yokota J, Ishida S, Hamada A, Kyotani S. Effect of particle size of nonsteroidal anti-inflammatory drug on lipopolysaccharide-induced inflammation on RAW264.7 cells. Int. J. Drug Dev. & Res. 10(3):20-4 (2018).
- Ishida S, Hamada S, Morimoto M, Yamakawa K, Suzue T, Okano Y. Assessment of drug loss and variation in divied weight after dispensing a pediatric dose of E Keppra® dry syrup 50%. Jpn. J. Pharm. Health Care Sci., 42(1):40-7 (2016).
- Ishida S, Motoike K, Okamoto Y, Yamakawa K, Watanabe T, Ando T, Suzue T and Okano Y. A simple method for administering Amitiza® capsule suspension through nasoentric feeding tubes. Jpn. J. Pharm. Health Care Sci., 40(5):285-90 (2014).