研究業績 | Laboratry of Molecular Nutrition and Toxicology

2022

1.Tony SR, Haque N, Siddique AE, Khatun M, Rahman M, Islam Z, Islam MS, Islam J, Hossain S, Hoque MA, Saud ZA,Sumi D, Wahed AS, Barchowsky A, Himeno S, Hossain K. Elevated serum periostin levels among arsenic-exposed individuals and their associations with the features of asthma. Chemosphere. 2022 Mar 9;298:134277. doi: 10.1016/j.chemosphere.2022.134277. Epub ahead of print. PMID: 35278445.

2. Himeno, S.,Fujishiro, H.,Sumi, D. Chapter 6: Bismuth. in “Handbook on the Toxicology of Metals, Volume II. Fifth Edition” (Eds. Nordberg, G. and Costa, M.) Elsevier, 2022.

3.Fujishiro, H., Miyamoto, S.,Sumi, D., Kambe, T., Himeno, S. Effects of individual amino acid mutations of zinc transporter ZIP8 on manganese- and cadmium-transporting activity. Biochem. Biophys. Res. Commun. (2022), 616: 6-32. https://doi.org/10.1016/j.bbrc.2022.05.068

4.Fujishiro, H., Sumino, M.,Sumi, D., Umemoto, H., Tsuneyama, K., Matsukawa, T., Yokoyama, K., Himeno, S. Spatial localization of cadmium and metallothionein in the kidneys of mice at the early phase of cadmium accumulation. J Toxicol Sci. 2022;47(12):507-517. doi: 10.2131/jts.47.507. PMID: 36450495.

5. Khatun, M., Siddique, A.E., Wahed, A.S., Haque, N., Tony, S.R., Islam, J., Alam, S., Sarker, M.K., Kabir, I., Hossain, S.,Sumi, D., Saud, Z.A., Barchowsky, A.,Himeno, S., Hossain K. Association between serum periostin levels and the severity of arsenic-induced skin lesions. PLoS One. 2023 Jan 4;18(1):e0279893. doi: 10.1371/journal.pone.0279893. PMID: 36598904; PMCID: PMC9812306.

2021

1. Ogawa ,M., Okamoto, Y., Himeno, S., Suzukawa,K., Sumi, D. Arsenite suppresses the transcriptional activity of EVI1 through the binding to CCHC-type Zn finger domain. Biochem Biophys Res Commun. 2020 Sep 3;529(4):910-915. doi: 10.1016/j.bbrc.2020.07.024. Epub 2020 Jul 29.

2. Sumi,D., Tsuyama, H., Ogawa,T., Ogawa, M., Himeno, S. Arsenitesuppresses IL-2-dependent tumoricidal activities of natural killer cells. Toxicol Appl Pharmacol. 2021 Feb 1;412:115353. doi: 10.1016/j.taap.2020.115353. Epub 2020 Dec 8.

3. Rahman, A., Islam, M. S.,Tony, S. R., Siddique, A. E., Mondal, V., Hosen, Z., Islam, Z., Hossain, M. I., Rahman,M.,Anjum,A., Paul, S. K., Hossen, F.,Sarker, M. K., Hossain, S., Salam, K. A., Haque, A.,Hoque, M. A.,Saud, Z. A., Xin, L.,Sumi,D., Himeno,S., Hossain, K. T helper 2-driven immune dysfunction in chronic arsenic-exposed individuals and its link to the featuresof allergic asthma. Toxicol Appl Pharmacol. 2021 Apr 9;115532. doi: 10.1016/j.taap.2021.115532.

4. Himeno, S.,Fujishiro, H. Roles of Zinc Transporters That Control the Essentiality and Toxicity of Manganese and Cadmium. Yakugakuzasshi 141 (5), 2021. doi: 10.1248/yakushi.20-00243-5. PMID: 33952754.

5. Fujishiro, H., Taguchi, H., Hamamo, S., Sumi,D., Himeno, S. 41. Comparisons of segment-specific toxicity of platinum-based agents and cadmium using S1, S2, and S3 cells derived from mouse kidney proximal tubules. Toxicology in vitro, 75: 105179. 2021 doi:10.1016/j.tiv.2021.105179. PMID: 33905841.

6. 藤代瞳、姫野誠一郎　「第6章攪乱第1節　腎臓におけるカドミウムとマンガンの輸送とその攪乱」生命金属ダイナミクス: 生体内における金属の挙動と制御　城　宜嗣、津本浩平　監修（エヌ・ティー・エス出版）2021年, pp313-319. 2021.

7. 角大悟，姫野誠一郎「環境化学物質および医薬品としてのヒ素化合物」生命金属ダイナミクス: 生体内における金属の挙動と制御　城宜嗣・津本浩平　監修，（エヌ・ティー・エス出版）2021年，pp. 334-340. 2021.

8. Homma-Takeda,S., Fujishiro,H., Tanaka,I., Yakumaru,H., Ayama,K., Uehara, A., Oikawa, M., Himeno, S., Ishihara, H. Single-Cell Imaging for Studies of Renal Uranium Transport and Intracellular Behavior.Minerals 11 (2), 191, 2021 https://doi.org/10.3390/min11020191

9. Sarker, MK., Tony, SR., Siddique, AE., Karim, MR., Haque, N., Islam, Z., Islam MS., Khatun, M., Islam, J., Hossain, S., Alam, Saud Z., Miyataka, H., Sumi, D., Barchowsky, A., Himeno, S., Hossain, K. Arsenic Secondary Methylation Capacity Is Inversely Associated with Arsenic Exposure-Related Muscle Mass Reduction. Int J Environ Res Public Health. 2021 Sep 15;18(18):9730. doi: 10.3390/ijerph18189730. PMID: 34574656; PMCID: PMC8472591.

10. Sarker, M. K., Tony, S. R., Siddique, A. E., Haque, N., Islam, M. S., Hossain, F., Islam, Z., Hossain, S., Hoque, M. A., Saud, Z. A.,Sumi, D., Himeno, S., Hossain, K. Gender differences in the risk of metabolic syndrome among chronic arsenic-exposed individuals in Bangladesh. Expo Health. (in press) 2021.

2020

1.Fujishiro, H., Yamamoto, H., Otera, N., Oka, N., Jinno, M., Himeno, S. In vitro evaluation of the effects of cadmium on endocytic uptakes of proteins into cultured proximal tubule epithelial cells. Toxics 8(2), E24 (2020) PMID: 32244724 PMCID: PMC7356949 DOI: 10.3390/toxics8020024

2019

1.Sumi, D., Yoshino, Y., Kameda, R., Himeno, S. Chronic exposure to submicromolar arsenite promotes the migration of human esophageal Het1A cells induced by heparin-binding EGF-like growth factor. Arch. Toxicol. 93(12), 3523 - 3534. (2019) [PubMed]
2.Fujishiro, H., Hamao, S., Isawa, M., Himeno, S. Segment-specific and direction-dependent transport of cadmium and manganese in immortalized S1, S2, and S3 cells derived from mouse kidney proximal tubules. J. Toxicol. Sci. 44(9), 611-619. (2019)　[PubMed]
3.Fujishiro, H., Himeno, S. Gene expression profiles of immortalized S1, S2, and S3 cells derived from each segment of mouse kidney proximal tubules. Fund. Toxicol. Sci. 6(4), 117-123. (2019) [J-STAGE]
4. Tsuyama, H.,Fujishiro, H., Himeno, S.,Sumi, D.Arsenite suppresses NO production evoked by lipopolysaccharide and poly(I:C) via the suppression of interferon-β expression in RAW264.7 cells. J. Toxicol. Sci. 44(2), 83-92. (2019) [PubMed]