2023
102. Prenylated-coumarins from Gmelina arborea and evaluation for neurotrophic activity.
M. Kubo, R. Irimajiri, M. Kawata, Y. Takahashi, K. Hayashi, M. Matsuno, K. Harada, N. Ikui, H. Mizukami, N. Kawahara, Y. Fukuyama. Phytochemistry 213, 113721 (2023).
101. Open and reusable annotated mass spectrometry dataset of a chemodiverse collection of 1600 plant exracts.
P.-M. Allard, A. Gaudry, L.-M. Quiros-Guerrero, A. Rutz, M. Dounoue-Kubo, T. W. N. Walker, E. Defossez, C. Long, A. Grondin, B. David, J.-L. Wolfender. GigaScience 12, 1-9 (2023).
2022
100. Transcriptome analysis of PC12 cells reveals that trans-banglene upregulates RT1-CE1 and downregulates abca1 in the neurotropic pathway.
M. Shoji, R. Okamoto, T. Unno, K. Harada, M. Kubo, Y. Fukuyama, T. Kuzuharada. Biol. Pharm. Bull. 45, 1784-1790 (2022).
99. Anchietins A-E: 30-norfriedelane-type triterpenes from Anchietea pyrifolia.
Y. Yoneda, T. Yahagi, K. Harada, Y. Okamoto, S. Motai, K. Matsuzaki, M. Kubo, Y. Fukuyama, A. Ohsaki. Phytochemistry 203, 113388 (2022).
98. Four clerodane diterpenoids from Ptychopetalum Olacoides.
M. Kubo, H. Tajima, W. Tang, K. Harada, Y. Fukuyama. Nat. Prod. Comm. 17, 1-6 (2022).
97. Germacrane-type sesquiterpenoids from Illicium lanceolatam.
M. Kubo, Y. Nishikawa, H. Nakagawa, S. Shimada, A. Mori, K. Harada, J.-M. Huang, A. Ohsaki, Y. Fukuyama. Tetrahedron Lett. 65, 132673 (2022).
2021
96. Total synthesis of (±)-spirotenuipesine A, a promoter of neurotrophic factor secretion from grial cells.
T. Yanagimoto, S. Yamada, Y. Kasai, H. Yamamoto, M. Kubo, Y. Fukuyama, H. Imagawa. Tetrahedron Lett. 64, 152723 (2021).
2020
95. Design and synthesis of dual active neovibsanin derivatives based on a chemical structure merging method.
T. Yanagimoto, S. Kishimoto, Y. Kasai, M. Kubo, H. Yamamoto, Y. Fukuyama, H. Imagawa. Bioorg. Med. Chem. Lett. 30, 127497 (2020).
94. The search for, and chemistry and mechanism of, neurotrophic natural products.
Y. Fukuyama, M. Kubo, K. Harada. J. Nat. Med. 74, 648-671 (2020).
93. Metabolite Profiling of Javanese Ginger Zingiber purpureum and Identification of Antiseizure Metabolites via a Low-Cost Open-Source Zebrafish Bioassay-Guided Isolation.
T. Brillatz, M. Kubo, S. Takahashi, N. Jozukuri, K. Takechi, E. F. Queiroz, L. Marcourt, P.-M. Allard, R. Fish, K. Harada, K. Ishizawa, A. D. Crawford, Y. Fukuyama, J.-L. Wolfender. J. Agric. Food. Chem. 68, 7904-7915 (2020).
92. Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation.
K. Hirano, M. Kubo, Y. Fukuyama, M. Namihira. Int. J. Mol. Sci. 21, Article 4772 (2020).
91. Chemistry and Neurotrophic Activities of (-)-Talaumidin and Its Derivatives.
K. Harada, M. Kubo, Y. Fukuyama. Front. Chem. 8, Article 301 (2020).
90. Develpoment of New Neurotrophic Compounds Based on Talaumidin.
K. Harada. Yakugaku Zasshi 140, 129-137 (2020).
89. The Challenge of a Female Scientist Studying Abroad with Her Children at the University of Geneva.
M. Kubo. Yakugaku Zasshi 140, 47-50 (2020).
88. Asymmetric Construction of Vicinal Stereocenters Containing Quaternary and Tertiary Carbons: Application to the Formal Synthesis of (-)-Chenopodene.
K. Harada, D. Ibaragi, Y. Edazawa, M. Sakashita, A. Nakata, M. Kubo, R. G. Carter, Y. Fukuyama. Eur. J. Org. Chem. 2020, 420 (2020).
[Highlighted at Front Cover]
87. cis-Banglene, a bangle (Zingiber purpureum)-derived bioactive compound, promotes mitochondrial biogenesis and glucose uptake by activating the IL-6/AMPK signaling pathway in C2C12 skeletal muscle cells.
T. Norikura, S. Kajiya, M. Sugawara, M. Kubo, Y. Fukuyama, S. Sato. J. Funct. Foods 64, 103632 (2020).
86. Serine protease inhibitors and activators from Dalbergia tonkinensis species.
N. T. Son, M. Suenaga, Y. Matsunaga, L. V. Chinh, M. Kubo, K. Harada, N. M. Cuong, Y. Fukuyama. J. Nat. Med. 74, 257-263 (2020).
2019
85. Taxonomically Informed Scoring Enhances Confidence in Natural Products Annotation.
A. Rutz, M. Dounoue-Kubo, S. Ollivier, J. Bission, M. Saesong, S. N. Ebrahimi, K. Ingkaninan, J.-L. Wolfender, P.-M. Allard. Front. Plant. Sci. 10, Article 1329 (2019).
84. Sucupiranins M-Q, five new furanocassane-type diterpenoids from the seeds of Bowdichia virgilioides.
Y. Endo, T. Kasahara, K. Asakura, M. Funasaki, G. Akisue, T. Etoh, K. Harada, Y. Fukuyama, K. Matsuzaki, M. Ishibashi, A. Ohsaki. Tetrahedron 75, 130511 (2019).
83. Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells.
M. Shoji, M. Ueda, M. Nishioka, H. Minato, M. Seki, K. Harada, M. Kubo, Y. Fukuyama, Y. Suzuki, E. Aoyama, M. Takigawa, T. Kuzuhara. Biochem. Biophys. Res. Commum. 519, 309-315 (2019).
82. Chemical Constituents of the Heartwood of Dalbergia tonkinensis.
N. T. Son, Y. Fukuyama, N. M. Cuong. Chem. Nat. Prod. 55, 854-856 (2019).
81. Chemical constituents of the Vietnamese plants Dalbergia tonkinensis Prain and Cratoxylum formosum (Jack) Dyer in Hook and their DPPH radical scavenging activities. N. T. Son, M. Kamiji, T. T. Huong, M. Kubo, N. M. Cuong, Y. Fukuyama. Med. Chem. Res. 28, 1441-1447 (2019).
80. Structure of seven new vibsane-type diterpenoids from Viburnum awabuki.
M. Kubo, M. Nakai, K. Harada, Y. Fukuyama. Tetrahedron 75, 2379-2384 (2019).
2018
79. Safety assessment of Bangle(Zingiber purpureum Rosc.) rhizome extract: Acute and chronic studies in rats and clinical studies in human.
E. Kato, M. Kubo, Y. Okamoto, Y. Matsunaga, H. Kyo, N. Suzuki, K. Uebara, Y. Fukuyama. ACS Omega 3, 15879-15889 (2018).
78. Enantioselective Synthesis of (-)-Halenaquinone.
S. Goswami, K. Harada, M. F. El-Mansy, R. Lingampally, R. G. Carter. Angew. Chem. Int. Ed. 57, 9117-9121 (2018).
77. Talaumidin promotes neurite outgrowth of staurosporine-differentiated RGC-5 cells through PI3K/Akt-dependent pathway.
Y. Koriyama, A. Furukawa, K. Sugitani, M. Kubo, K. Harada, Y. Fukuyama. Adv. Exp. Med. Biol. 1074, 649-653 (2018).
76. Chemotaxonomic aspects of the constituents of the plant Dalbergia.
N. T. Son, T. Yamamoto, Y. Fukuyama. Biochem. Sys. Eco. 78, 98-101 (2018).
75. Structure-activity relationships of talaumidin derivatives: Their neurite-outgrowth
promotion in vitro and optic nerve regeneration in vivo.
K. Harada, K. Zaha, R. Bando, R. Irimaziri, M. Kubo, Y. Koriyama, Y. Fukuyama.
Eur. J. Med. Chem. 148, 86-94 (2018).
74. Antimicrobial activity of the constituents of Dalbergia tonkinensis and structural-bioactive highlights.
N. T. Son, M. Oda, N. Hayashi, D. Yamaguchi, Y. Kawagishi, F. Takahashi,
K. Harada, N. M. Cuong, Y. Fukuyama. Nat. Prod. Comm. 13, 157-161 (2018).
2017
73. Three new bibenzyls from the twigs of Smilax longifolia.
Y. Imura, K. Harada, M. Kubo, Y. Fukuyama. Nat. Prod. Comm. 12, 1877-1879 (2017).
72. Sucupiranins A-L, furanocassane diterpenoids from the seeds of Bowdichia virgilinoids.
Y. Endo, T. Kasahara, K. Harada, M. Kubo, T. Etoh, M. Ishibashi, A. Ishiyama, M. Iwatsuki, K. Otoguro, S. Omura, G. Akisue, T. Hirano, H. Kagechika, Y. Fukuyama, A. Ohsaki. J. Nat. Prod. 80, 3128-3135 (2017).
71. Two new carboxyethylflavanones from the heartwood of Dalbergia tonkinensis and their antimicrobial activities.
N. T. Son, Harada, N. M. Cuong, Y. Fukuyama. Nat. Prod. Comm. 12, 1721-1723 (2017).
70. Studies on extraction conditions to increase the content of neurotrophic compounds in the Bangle (Zingiber purpurem).
M. Kubo, S. Kaga, K. Harada, Y. Okamoto, E. Kato, S. Hosoda, Y. Fukuyama. Nat. Prod. Comm. 12, 1287-1289 (2017).
69. Construction of canthin-5,6-diones via termolecular condensation reaction: Studies on synthesis of amarastelline A.
K. Harada, H. Yamane, M. Kubo, A. Ohsaki, Y. Fukuyama. Nat. Prod. Comm. 12, 1231-1233 (2017).
68. Chemical constituents from Hericium erinaceus promote neuronal survival and potentiate neurite outgrowth via the TrkA/Erk1/2 pathway.
C.-C. Zhang, C.-Y. Cao, M. Kubo, K. Harada, Y. Fukuyama, J.-M. Gao. Int. J. Mol. Sci. 18, 1659-1671 (2017).
2016
67. Six new triterpenoidsnfrom the aerial parts of Maytenus divrsifolia.N. Anoda, M. Matsunaga, M. Kubo, K. Harada, Y. Fukuyama. Nat. Prod. Comm. 11, 1085-1088 (2016).
66. A new pimarane-type diterpenoid from the seeds of Bowdichia virgilioides.
M. Kubo, M. Uemura, K. Harada, A. Ohsaki, Y. Fukuyama. Nat. Prod. Comm. 11, 917-919 (2016).
65. Antimalarial phenanthroindolizine alkaroids from Ficus septica.
M. Kubo, W. Yatsuzuka, S. Matsushima, K. Harada, Y. Inoue, H. Miyamoto, M. Matsumoto, Y. Fukuyama. Chem. Pharm. Bull. 64, 957-9603 (2016)
64. Bangle (Zingiber purpureum) improves spatial learning, reduces deficits in memory, and promotes neurogenesis in the dentate gyrus of senescence-accelerated mouse P8.
M. Nakai, M. Iizuka, N. Matsui, K. Hosogi, A. Imai, N. Abe, H. Shiraishi, A. Hirata, Y. Yagi, K. Jobu, J. Yokota, E. Kato, S. Hosoda, S. Yoshioka, K. Harada, M. Kubo, Y. Fukuyama, M. Miyamoto. J. Med. food 19, 435-441 (2016).
63. Neurotrophic activity of jiadifenolide on neuronal precursor cells derived from human induced pluripotent stem cells.
M. Shoji, M. Nishioka, H. Minato, K. Harada, M. Kubo, Y. Fukuyama, T. Kuzuhara. Biochem. Biophys. Res. Comm. 470, 798-803 (2016).
62. Anti-biofilm and bactericidal effects of magnolia bark-derived magnolol and honokiol on Streptococcus mutans.
Y. Sakaue, H. Domon, M. Oda, S. Takenaka, M. Kubo, Y. Fukuyama, T. Okiji, Y. Terao. Microbiol. Immunol. 60, 10-16 (2016).
2015
61. Search of Neurotrophin-mimic Natural Products for Prevention and Treatment of Neurodegenerative disease.M. Kubo. Yakugaku Zasshi 135 1147-1152 (2015).
60. Synthetic Studies of Neurite Outgrowth-Promoting Neovibsanins.
H. Imagawa, T. Esumi, Y. Fukuyama. J. Syn. Org. Chem. Jpn.73, 902-910 (2015).
59. Systematic Asymmetric Synthesis of All Diastereomers of (-)-Talaumidin and Their Neurotrophic Activity.
K. Harada, M. Kubo, H. Horiuchi, A. Ishii, T. Esumi, H. Hioki, Y. Fukuyama. J. Org. Chem. 80. 7076-7088 (2015).
58. Tetranorsesquiterpenoids and Santalane-Type Sesquiterpenoids from Illicium lanceolatum and Their Antimicrobial Activity against the Oral Pathogen Porphyromonas gingivalis.
M. Kubo, Y. Nishikawa, K. Harada, M. Oda, J.-M. Huang, H. Domon, Y. Terao, Y. Fukuyama. J. Nat. Prod., 78. 1466-1469 (2015).
57. Nonpeptide neurotrophic agents useful in the treatment of neurodegenerative diseases such as Alzheimer's disease.
M. Akagi, N. Matsui, H. Akae, N. Hirashima, N. Fukuishi, Y. Fukuyama, R. Akagi. J. Pharm. Sci.127, 155-163 (2015).
56. Synthesis of jiadifenin using Mizoroki-Heck and Tsuji-Trost reactions.
K. Harada, A. Imai, K. Uto, R. G. Carter, M. Kubo, H. Hioki, Y. Fukuyama.
Tetrahedron, 71. 2199-2209 (2015).
55. Novel neurotrophic phenylbutenoids from Indonesian ginger Bangle, Zingiber purpureum.
M. Kubo, M. Gima, K. Baba, M. Nakai, K. Harada, M. Suenaga, Y. Matsunaga,
E. Kato, S. Hosoda, Y. Fukuyama. Bio. Med. Chem. Lett., 25. 1586-1591 (2015).
2014
54. Efficient synthesis of neurotrophic honokiol using Suzuki-Miyaura reactions.
K. Harada, C. Arioka, A. Miyakita, M. Kubo, Y. Fukuyama. Tetrahedron Lett., 55. 6001-6003 (2014).
53. Solid-phase synthesis of benzazoles, quinazolines, and quinazolinones using an alkoxyamine linker.
K. Yamaguchi, T. Noda, Y. Higuchi, N. Aoki, R. Yamaguchi, M. Kubo, K. Harada, Y. Fukuyama, H. Hioki. Tetrahedron Lett., 55. 5793-5797 (2014).
52. A lanostane Triterpenoid ans Tree Cholestane Steroids from Tilia kiustana.
M. Shimada, M. Ozawa, K. Iwamoto, Y. Fukuyama, A. Kishida, A. Ohsaki. Chem. Pharm. Bull., 62. 937-941 (2014).
51. Chapter 2 - Chemical Diversity of Vibsanin-Type Diterpenoids and Neurotrophic
Acitivity and Synthesis of Neovibsanin.
M. Kubo, T. Esumi, H. Imagawa, Y. Fukuyama. Studies in Natural Products Chemistry., 43. 41-78 (2014).
50. A New Spiroindene Pigment from the Medicinal Fungus Phellinus ribis.
M. Kubo, Y. Liu, M. Ishida, K. Harada, Y. Fukuyama. Chem. Pharm. Bull., 62. 122-124 (2014).
2013
49. A Short Synthesis of (+)-Bakuchiol.
T. Esumi, C. Yamamoto, Y. Fukuyama. Synlett, 24. 1845-1847 (2013).
48. Total Synthesis of Bisbibenzyl Dibenzofuran Asterelin A via Intramolecular Oxidative Coupling.
K. Makino, K. Harada, M. Kobo, H. Hioki, Y. Fukuyama. Nat. Prod. Comm., 8. 915-918 (2013).
47. Total synthesis of riccardin C and (±)-cavicularin via Pd-catalyzed Ar-Ar corss couplings.
K. Harada, K. Makino, N. Shima, H. Okuyama, T. Esumi, M. Kubo, H. Hioki, Y. Asakawa, Y. Fukuyama.
Tetrahedron, 69. 6959-6968 (2013).
46. Evaluation of Constituents fo Piper retrofractum Fruits on Neurotrophic Activity.
M. Kubo, R. Ishii, Y. Ishino, K. Harada, N. Matsui, M. Akagi, E. Kato, S. Hosoda, Y. Fukuyama.
J. Nat. Prod., 76. 769-773 (2013).
45. Construction of Successive Chiral Centers Adjacent to a Chiral Tetraalkylated Quaternary Center Using an Asymmetric Aldol Reaction.
T. Esumi, C. Yamamoto, Y. Tsugawa, M. Toyota, Y. Asakawa, Y. Fukuyama.
Org. Lett., 15, 1898-1901 (2013).
2012
44. Nerve Growth Factor-Potentiating Benzofuran Derivatives from the Medicinal Fungus Phellinus ribis.
Y. Liu, M. Kubo, Y. Fukuyama.
J. Nat. Prod., 75, 2152-2157 (2012).
43. Solid-phase synthesis of benzothazoles using an alkoxyamine linker.
H. Hioki, K. Matsushita, T. Noda, K. Yamaguchi, M. Kubo, K. Harada, Y. Fukuyama.
Tetrahedron Lett., 53, 4337-4342 (2012).
42. Spirocyclic nortriterpenoids with NGF-potentiating activity from the fruits of Leonurus heterophyllus.
Y. Liu, M. Kubo, Y. Fukuyama,
J. Nat. Prod., 75, 1353-1358 (2012).
41. Magnolol protects against MPTP/MPP+-Induced toxicity via Inhibition of oxidative stress in In vivo and In vitro models of parkinson's disease.
A. Muroyama, A. Fujita, Cheng Lv, S. Kobayashi,Y. Fukuyama, Y. Mitsumoto,
Parkinson's Disease., 2012, article ID 985157.
40. Phenylbutenoid dimers isolated from Zingiber purureum exert neurotropic effects on cultured neurous and enhance hippocampal neurogenesis in olfactory bulbectomized mice.
N. Matsui, Y. Kido, H. okada, M. Kubo, M. Nakai, N. Fukuishi, Y. Fukuyama, M. Akagi,
Neuroscience. Lett., 513, 72-77 (2012).
39. Syntheses of structurally-simplified and fluorescently-labeled neovibsanin derivatives and analysis of their neurite outgrowth activity in PC12 cells.
H. imagawa, H. Saijo, H. Yamaguchi, K. Maekawa, T. Kurisaki, H. Yamamoto, M. Nishizawa, M. Oda, M. Kabura, M. Nagahama, J. Sakurai, M. Kubo, M. Nakai, K. Makino, M. Ogata, H.Takahashi, Y. Fukuyama,
Bioorg. Med. chem. Lett., 22, 2089-2093 (2012).
38. The first examples of seco-prezizaane-type norsesquiterpenoides with neurotrophic activity from Illicium jiadifengpi.
M. Kubo, K. Kobayashi, J.-M. Huang, K. Harada, Y. Fukuyama,
Tetrahedron Lett., 53, 1231-1235 (2012).
2011
37. New Prenylated C6-C3 Compounds from the Twigs of Illicium anisatum.
M. Kubo, N. Shima, K. Harada, H. Hioki, Y. Fukuyama,
Chem. Pharm. Bull., 59, 898-901 (2011).
36. Asymmetric synthesis of (-)-chicanine using a highly regioselective intramolecular Mitsunobu reaction and revision of its absolute configuration.
K. Harada, H. Horiuchi, K. Tanabe, R. G. Carter, T. Esumi, M, Kubo, H. Hioki, Y. Fukuyama
Tetrahedron Lett., 52, 3005-3008 (2011).
35. Eight New Clerodane Diterpenoids from the Bark of Ptychopetalum olacoides.
W. Tang, K. Harada, M. Kubo, H. Hioki, Y. Fukuyama,
Nat. Prod. Comm., 6, 327-332 (2011).
34. Asymmetric Synthesis of (+)-Machilin F by Unusual Stereoselective Mitsunobu Reaction.
K. Harada, N. Kubo, K. Tanabe, M. Kubo, T. Esumi, H. Hioki, Y. Fukuyama,
Heterocycles, 82, 1127-1132 (2011).
33. Synthesis of the ABC Ring System of Jiadifenin via Pd-Catalyzed Cyclizations.
K. Harada, A. Imai, K. Uto, R. G. Carter, M. Kubo, H. Hioki, Y. Fukuyama
Org. Lett., 13, 988-991 (2011).
2010
32. Chemistry and biological activities of vibsanine-type diterpenoids.
Y. Fukuyama, M. Kubo, T. Esumi, K. Harada, H. Hioki.
Heterocycles, 81, 1571-1602 (2010).
31. Novel Alkoxyamine Linker to Load Ketones for Solid-Phase Synthesis: Application of the Synthesis of 1,4-Benzodiazepine-2-ones.
K. Matsushita, C. Okamoto, M. Yoshimoto, K. Harada, M. Kubo, Y. Fukuyama, H. Hioki,
J. Comb. Chem., 12, 311-314 (2010).
30. NGF-potentiating vibsane-type diterpenoids from Viburnum sieboldii.
M. Kubo, Y. Kishimoto, K. Harada, H. Hioki, Y. Fukuyama,
Bioorg. Med. Chem. Lett., 20, 2566-2571 (2010).
29. First enantiocontrolled formal synthesis of (+)-neovibsanin B, a neurotrophic diterpenoid.
T. Esumi, T. Mori, M. Zhao, M. Toyota, Y. Fukuyama,
Org. Lett., 12, 888-891 (2010).
2009
28. Discovery of hydrolytic catalysts in a peptidocalixarene library by binding assay with a transition state analogue for the hydrolysis.
H. Hioki, R. Nishimoto, K. Kawaguchi, M. Kubo, K. Harada, Y. Fukuyama.
Chem. Comm., 7194-7196 (2009).
27. Novel pentacyclic seco-prezizaane-type sesquiterpenoids with neurotrophic properties from Illicium jiadifengpi.
M. Kubo, C. Okada, J.-M. Huang, K. Harada, H. Hioki, Y. Fukuyama.
Org. Lett., 11, 5190-5193 (2009).
26. Isolation, synthesis, and outgrowth-promoting activity of illicinin A from the flowers of Illicium anisatum.
S. Takaoka, N. Takaoka, Y. Minoshima, J.-M. Huang, M. Kubo, K. Harada, H. Hioki, Y. Fukuyama.
Tetrahedron, 65, 8354-8361 (2009).
25. Sweet and bitter constituents of Wilbrandia species.
M. Ochi, K. Moriyama, K. Ohmae, Y. Fukuyama, K. Nihei, I. Kubo.
Food Chem., 115, 61-65 (2009).
24. Total Synthesis of Pseudodehydrothyrsiferol.
H. Hioki, M. Motosue, Y. Mizutani, A. Noda, T. Shimoda, M. Kubo, K. Harada, Y. Fukuyama, M. Kodama.
Org. Lett., 11, 579-582 (2009).
23. Novel NGF-potentiating diterpenoids from a Brazilian medicinal plant, Ptychopetalum olacoides.
W. Tang, M. Kubo, K. Harada, H. Hioki, Y.Fukyama.
Bioorg. Med. Chem. Lett., 19, 882-886 (2009).
22. Synthesis of riccardin C and its seven analogues. Part 1: The role of their phenolic hydroxy groups as LXRα agonists.
H. Hioki, N. shima, K. Kawaguchi, K. Harada, M. Kubo, T. Esumi, T. Nishimaki-Mogami, J. Sawada, T. Hashimoto, Y. Asakawa, Y.Fukyama.
Bioorg. Med. Chem. Lett., 19, 738-741 (2009).
2008
21. Efficient construction of a chiral all-carbon quaternary center by asymmetric 1,4-addition and its application to total synthesis of (+)-bakuchiol.
T. Esumi, H. Shimizu, A. Kashiyama, C. Sasaki, M. Toyota, Y. Fukyama.
Tetrahedron Lett., 49, 6846-6849 (2008).
20. Clerodane Diterpenoids with NGF-Potentiating Activity from Ptychopetalum olacoides.
W. Tang, H. Hioki, K. Harada, M. Kubo, Y. Fukuyama.
J. Nat. Prod., 71, 1760-1763 (2008).
19. Solid-phase combinatorial synthesis of 2-arylquinazolines and 2-arylquinazolinones by an 4-alkoxyaniline linker.
H. Hioki, K. Matsushita, S. Nakamura, H. Horiuchi, M. Kubo, K. Harada, Y. Fukuyama.
J. Comb. Chem., 10, 620-623 (2008).
18. Synthesis of (-)-talaumidin, a neurotrophic 2,5-biaryl-3,4-dimethyltetrahydrofuran lignan, and its stereoisomers.
Y. Fukuyama, K. Harada, T. Esumi, D. Hojyo, Y. Kujime, N. Kubo, M. Kubo, H. Hioki.
Heterocycles., 76, 551-567 (2008)
17. Two New Sesquiterpenoids and Two New Prenylated Phenylpropanoids from Illicium fargesii, and Neuroprotective Activity of Macranthol. M. Moriyama, J.-M. Huang, C.-S. Yang, M. Kubo, K. Harada, H. Hioki, Y. Fukuyama, Chem. Pharm. Bull., 56, 1201-1204 (2008).
16. Synthetic studies toward neovibsanins A and B: construction of the neovibsanin core utilizing palladium(0)-catalyzed carbonylative cyclization with carbon monoxide. T. Esumi, M. Zhao, T. Kawakami, M. Fukumoto, M. Toyota, Y. Fukuyama, Tetrahedron Lett., 49, 2692-2696 (2008).
2007
15. Antioxidant Phenylpropanoid-Substituted Epicatechins from Trichilia catigua. W. Tang, H. Hioki, K. Harada, M. Kubo, Y. Fukuyama, J. Nat. Prod., 70, 2010-2013 (2007).
14.Solid-phase combinatorial synthesis of benzothiazoles, benzimidazoles, and benzoxazoles using a traceless linker. H. Hioki, K. Matsushita, M. Kubo, K. Harada, M. Kodama, Y. Fukuyama, Tetrahedron, 63, 11315-11324 (2007).
13. An efficient synthesis of the CD rings model for merrilactone A. K. Harada, H. Ito, H.Hioki, Y. Fukuyama, Tetrahedron Lett., 48, 6105-6108 (2007).
12. ビブサン型ジテルペンの化学と生物活性．福山愛保，江角朋之．有機合成化学協会誌. 65. 585-597 (2007).
11. Structure and neurotrophic activity of novel sesqui-neolignans from the pericarps of Illicium fargesii. M. Moriyama, J.-M. Huang, C.-S. H. Hioki, M. Kubo, K. Harada, Y. Fukuyama, Tetrahedron, 63, 4243-4249 (2007).
10. Total Synthesis and Bioactivity of an Unnatural Enantiomer of Merrilactone A: Development of an Enantioselective Desymmetrization Strategy. M. Inoue, N. Lee, S. Kasuya, T. Sato, M. Hirama, M. Moriyama, Y. Fukuyama, J. Org. Chem., 72, 3065-3075 (2007).
9. 神経毒と神経突起、栄養因子活性物質．天然物化学ー植物編ー、アイピーシー、福山愛保、pp.183-197 (2007).
2006
8. Two Diterpene Rhamnosides, Mimosasides B and C, from Mimosa hostilis. A. Ohsaki, R. Yokoyama, H. Miyake, Y. Fukuyama, Chem. Pharm. Bull., 54, 1728-1729 (2006).
7. First enantioselective synthesis of (-)-talaumidin, a neurotrophic diaryltetrahydrofuran-type lignan. T. Esumi, D. Hojyo, H. Zhai, Y. Fukuyama, Tetrahedron Lett., 47, 3979-3983 (2006).
6. A Norbergenin Derivative Inhibits Neuronal Cell Damage Induced by Tunicamycin. S. Suzuki, Y. Okuse, M. Kawase, Y. Fukuyama, H. Takahashi, M. Sato, Bio. Pharm. Bull., 29, 1335-1338 (2006).
5. Combinatorial synthesis of Benzothiazoles and benzimidazoles using a traceless aniline linker. H Hioki, K. Matsushita, M. Kubo, M. Kodama, J. Comb. Chem., 8, 462-463 (2006).
4. Neovibsanin F and its congeners, rearranged vibsanin-type diterpenes from Viburnum suspensum. Y. Fukuyama, H. Fujii, H. Minami, H. Takahashi, M. Kubo, J. Nat. Prod., 69, 1098-1100 (2006).
3. Degraded and Oxetane-Bearing Limonoids from the Roots of Melia azedarach. Y. Fukuyama, M. Nakaoka, T. Yamamoto, H. Takahashi, H. Minami, Chem. Pharm. Bull., 54, 1219-1222 (2006).
2. On-bead screening of a library to detect host?guest complexation by an aniline reporter. M. Kubo, R. Nishimoto, M. Doi, M. Kodama, H. Hioki, Chem. Commun., 3390-3392 (2006).
1. Development of calixarene-based host molecules for peptides in aqueous media. M. Kubo, E. Nashimoto, T. Tokiyo, Y. Morisaki, M. Kodama, H. Hioki, Tetrahedron Lett., 47, 1927-1931 (2006).