2015年

原著論文

Base pair recognition ability of 2-(methylamino)pyrimidin-4-yl nucleobase in parallel triplex DNA
Yoshiyuki Hari*, Satoshi Kashima, Yuya Matsuda, Akihiro Sakata, Ryutato Takamine, Shin Ijitsu, Satoshi Obika*
Heterocycles (Invited) 2015, 90, 432-441 (doi:10.3987/COM-14-S(K)41).

2014年

原著論文

Sulfonamide-bridged nucleic acid: Synthesis, High RNA selective hybridization, and high nuclease resistance
Yasunori Mitsuoka, Yuko Fujimura, Reiko Waki, Akira Kugimiya, Tsuyoshi Yamamoto, Yoshiyuki Hari, Satoshi Obika*
Org. Lett. 2014, 16, 5640-5643 (doi:10.1021/ol503029v).

Synthesis of oligonucleotides containing N,N-disubstituted 3-deazacytosine nucleobases by post-elongation modification and their triplex-forming ability with double-stranded DNA
Masaaki Akabane-Nakata, Satoshi Obika*, Yoshiyuki Hari*
Org. Biomol. Chem. 2014, 12, 9011-9015 (doi:10.1039/c4ob01760a).

Kinetic study of the binding of triplex-forming oligonucleotides containing partial cationic modifications to double-stranded DNA
Yoshiyuki Hari*, Shin Ijitsu, Masaaki Akabane-Nakata, Takuya Yoshida, Satoshi Obika*
Bioorg. Med. Chem. Lett. 2014, 24, 3046-3049 (doi:10.1016/j.bmcl.2014.05.031).

Guanidine bridged nucleic acid (GuNA): an effect of a cationic bridged nucleic acid on DNA binding affinity
Ajaya R. Shrestha, Yutaro Kotobuki, Yoshiyuki Hari, Satoshi Obika*
Chem. Commun. 2014, 50, 575-577 (doi:10.1039/c3cc46017g).

The ability of 1-aryltriazole-containing nucleobases to recognize a TA base pair in triplex DNA
Yoshiyuki Hari*, Motoi Nakahara, Shin Ijitsu, Satoshi Obika*
Heterocycles (Invited) 2014, 88, 377-386 (doi:10.3987/COM-13-S(S)33).

2013年

原著論文

2',4'-BNA bearing a chiral guanidinopyrrolidine-containing nucleobase with potent ability to recognize the CG base pair in parallel-motif DNA triplex
Yoshiyuki Hari*, Masaaki Akabane, Satoshi Obika*
Chem. Commun. 2013, 49, 7421-7423 (doi:10.1039/c3cc44030c).

Synthesis and properties of 2'-O,4'-C-ethyleneoxy bridged 5-methyluridine
Yoshiyuki Hari*, Tomohiko Morikawa, Takashi Osawa, Satoshi Obika*
Org. Lett. 2013, 15, 3702-3705 (doi:10.1021/ol401566r).

Synthesis of novel polyesteramine dendrimers by divergent and convergent methods
Hitoshi Akiyama, Kazuyuki Miyashita, Yoshiyuki Hari, Satoshi Obika*, Takeshi Imanishi
Tetrahedron 2013, 69, 6810-6820 (doi:10.1016/j.tet.2013.06.024).

Triplex-forming ability of oligonucleotides containing 1-aryl-1,2,3-triazole nucleobases linked via a two atom-length spacer
Yoshiyuki Hari*, Motoi Nakahara, Satoshi Obika*
Bioorg. Med. Chem. 2013, 21, 5583-5588 (doi:10.1016/j.bmc.2013.05.034).

Base-pair recognition ability of hydroxyphenyl nucleobases in parallel triplex DNA
Yoshiyuki Hari*, Satoshi Kashima, Hiroyasu Inohara, Shin Ijitsu, Takeshi Imanishi, Satoshi Obika*
Tetrahedron 2013, 69, 6381-6391 (doi:10.1016/j.tet.2013.05.107).

Synthesis and properties of thymidines with six-membered amide bridge
Yoshiyuki Hari, Takashi Osawa, Yutaro Kotobuki, Ajaya R. Shrestha, Aiko Yahara, Satoshi Obika*
Bioorg. Med. Chem. 2013, 21, 4405-4412 (doi:10.1016/j.bmc.2013.04.049).

総説

三重鎖核酸形成時に二重鎖DNA中のCG塩基対を認識可能な人工核酸の開発
張 功幸*
Yakugaku Zasshi (Invited) 2013, 133, 1201-1208 (doi:10.1248/yakushi.13-00215).

2012年

原著論文

A 2-amino-6-methylpyridin-5-yl nucleobase for GC base pair recognition in the parallel triplex DNA
Motoi Nakahara, Yoshiyuki Hari*, Satoshi Obika
Heterocycles (Invited) 2012, 86, 1135-1146 (doi:10.3987/COM-12-S(N)68).

Synthesis and duplex-forming ability of oligonucleotides containing 4’-carboxythymidine analogs
Yoshiyuki Hari, Takashi Osawa, Satoshi Obika*
Org. Biomol. Chem. (Invited) 2012, 10, 9639-9649 (doi:10.1039/c2ob26712h).

Amido-bridged nucleic acid (AmNA): Synthesis, duplex stability, nuclease resistance, and in vitro antisense potency
Aiko Yahara, Ajaya R. Shrestha, Tsuyoshi Yamamoto, Yoshiyuki Hari, Takashi Osawa, Masaki Yamaguchi, Masaru Nishida, Tetsuya Kodama, Satoshi Obika*
ChemBioChem 2012, 13, 2513-2516 (doi:10.1002/cbic.201200506).

総説

Towards the sequence-selective recognition of double-stranded DNA containing pyrimidine-purine interruptions by triplex-forming oligonucleotides
Yoshiyuki Hari*, Satoshi Obika, Takeshi Imanishi*
Eur. J. Org. Chem. (Invited) 2012, 2012, 2875-2887 (doi:10.1002/ejoc.201101821).

2011年

原著論文

Synthesis and properties of a bridged nucleic acid with a perhydro-1,2-oxazin-3-one ring
Ajaya R. Shrestha, Yoshiyuki Hari, Aiko Yahara, Takashi Osawa, Satoshi Obika*
J. Org. Chem. 2011, 76, 9891-9899 (doi:10.1021/jo201597e).

A 4-[(3R,4R)-dihydroxypyrrolidino]pyrimidin-2-one nucleobase for a CG base pair in triplex DNA
Yoshiyuki Hari*, Masaaki Akabane, Yuri Hatanaka, Motoi Nakahara, Satoshi Obika*
Chem. Commun. 2011, 47, 4424-4426 (doi:10.1039/c1cc10138b).

Synthesis and triplex-forming ability of oligonucleotides bearing 1-substituted 1H-1,2,3-triazole nucleobases
Yoshiyuki Hari*, Motoi Nakahara, Juanjuan Pang, Masaaki Akabane, Takeshi Kuboyama, Satoshi Obika*
Bioorg. Med. Chem. 2011, 19, 1162-1166 (doi:10.1016/j.bmc.2010.12.049).

洋書

2’-O,4’-C-Methyleneoxymethylene bridged nucleic acid (2’,4’-BNA^COC)
Yoshiyuki Hari, Tetsuya Kodama, Takeshi Imanishi, Satoshi Obika
Therapeutic Oligonucleotides, J. Goodchild (ed.), Humana Press, 31-57 (2011).

1-Diazo-1-silylalkanes (Update 2010)
Yoshiyuki Hari, Toyohiko Aoyama, Takayuki Shioiri
Science of Synthesis Knowledge Updates 2010/4, M. Oestreich (vol ed.), Georg Thieme Verlag, 325-68 (2011).

2010年

原著論文

Facile synthesis of 1-methyl-1H-benzo[b]azepines from 1-methylquinolinium iodides and diazo(trimethylsilyl)methylmagnesium bromide
Mikio Morita, Yoshiyuki Hari*, Toyohiko Aoyama
Synthesis 2010, 4221-4227 (doi:10.1055/s-0030-1258306).

2’,4’-BNA bearing a 2-pyridine nucleobase for CG base pair recognition in the parallel motif triplex DNA
Yoshiyuki Hari*, Sachiko Matsugu, Hiroyasu Inohara, Yuri Hatanaka, Masaaki Akabane, Takeshi Imanishi, Satoshi Obika*
Org. Biomol. Chem. 2010, 8, 4176-4180 (doi:10.1039/c004895j).

Synthesis of 3-substituted 3-(trimethylsilyl)pyrrolidines from β-aminoketones and lithium trimethylsilyldiazomethane
Yoshiyuki Hari, Takuya Yokoyama, Toyohiko Aoyama*
Heterocycles (Invited) 2010, 80, 679-687 (doi:10.3987/COM-09-S(S)70).

2009年

原著論文

Facile synthesis of 2-unsubstituted benzofuran-3-carboxylates using diazo(trimethylsilyl)methylmagnesium bromide
Yoshiyuki Hari*, Ryosuke Kondo, Koji Date, Toyohiko Aoyama*
Tetrahedron 2009, 65, 8708-8713 (doi:10.1016/j.tet.2009.08.041).

The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation
Gil Tae Hwang, Yoshiyuki Hari, Floyd E. Romesberg*
Nucleic Acids Res. 2009, 37, 4757-4763 (doi:10.1093/nar/gkp467).

Facile two-step synthesis of 3-substituted indazoles using diazo(trimethylsilyl)methylmagnesium bromide
Yoshiyuki Hari*, Ryosuke Sone, Toyohiko Aoyama*
Org. Biomol. Chem. 2009, 7, 2804-2808 (doi:10.1039/b907796k).

Synthesis and base-pairing properties of C-nucleotides having 1-substituted 1H-1,2,3-triazoles
Motoi Nakahara, Takeshi Kuboyama, Akihiro Izawa, Yoshiyuki Hari*, Takeshi Imanishi, Satoshi Obika*
Bioorg. Med. Chem. Lett. 2009, 19, 3316-3319 (doi:10.1016/j.bmcl.2009.04.063).

A bridged nucleic acid, 2’,4’-BNA^COC: Synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2’,4’-BNA^COC monomers and RNA-selective nucleic-acid recognition
Yasunori Mitsuoka, Tetsuya Kodama, Ryo Ohnishi, Yoshiyuki Hari, Takeshi Imanishi, Satoshi Obika*
Nucleic Acids Res. 2009, 37, 1225-1238 (doi:10.1093/nar/gkn1062).

総説

トリメチルシリルジアゾメタンを用いる複素環化合物の合成
張 功幸*，塩入孝之，青山豊彦*
J. Synth. Org. Chem., Jpn. (Invited) 2009, 67, 357-368 (doi:10.5059/yukigoseikyokaishi.67.357).

2008年

原著論文

Optimization of the pyridyl nucleobase scaffold for polymerase recognition and unnatural base pair replication
Yoshiyuki Hari, Gil Tae Hwang, Aaron M. Leconte, Nicolas Joubert, Michal Hocek, Floyd E. Romesberg*
ChemBioChem 2008, 9, 2796-2799 (doi:10.1002/cbic.200800577).

New synthesis of t-butyl arylpropiolates using diazo(trimethylsilyl)methylmagnesium bromide
Yoshiyuki Hari, Koji Date, Ryosuke Kondo, Toyohiko Aoyama*
Tetrahedron Lett. 2008, 49, 4965-4967 (doi:10.1016/j.tetlet.2008.05.155).

Synthesis of chiral tetrahydroisoquinoline-derived b-amino alcohols and their application to asymmetric reaction
Yoshiyuki Hari, Masaki Sakuma, Ayako Miyakawa, Keiichiro Hatano, Toyohiko Aoyama*
Heterocycles (Invited) 2008, 76, 305-311 (doi:10.3987/COM-08-S(N)9).

Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet
Aaron M. Leconte, Gil Tae Hwang, Shigeo Matsuda, Petr Capek, Yoshiyuki Hari, Floyd E. Romesberg*
J. Am. Chem. Soc. 2008, 130, 2336-2343 (doi:10.1021/ja078223d).

Recognition of T•A interruption by 2',4'-BNAs bearing heteroaromatic nucleobases through parallel motif triplex formation
Satoshi Obika, Hiroyasu Inohara, Yoshiyuki Hari, Takeshi Imanishi*
Bioorg. Med. Chem. 2008, 16, 2955-2967 (doi:10.1016/j.bmc.2007.12.043).

Facile synthesis of 2-azaazulenes from thiobenzoyl isocyanates using trimethylsilyldiazomethane
Mikio Morita, Yoshiyuki Hari, Tomoe Iguchi, Toyohiko Aoyama*
Tetrahedron 2008, 64, 1753-1758 (doi:10.1016/j.tet.2007.11.107).

2007年

原著論文

Facile one-pot synthesis of functionalized acetylenes from aryl and heteroaryl aldehydes using lithium trimethylsilyldiazomethane
Yoshiyuki Hari, Koji Date, Toyohiko Aoyama*
Heterocycles (Invited) 2007, 74, 545-552 (doi:10.3987/COM-07-S(W)32).

An efficient synthesis of 2-diazo-2-(trimethylsilyl)ethanols and their application to pyrazole synthesis
Yoshiyuki Hari, Susumu Tsuchida, Ryosuke Sone, Toyohiko Aoyama*
Synthesis 2007, 3371-3375 (doi:10.1055/s-2007-990817).

2006年

原著論文

Stability and polymerase recognition of pyridine nucleobase analogues: Role of minor-groove H-bond acceptors
Yoonkyung Kim, Aaron M. Leconte, Yoshiyuki Hari, Floyd E. Romesberg*
Angew. Chem. Int. Ed. 2006, 45, 7809-7812 (doi:10.1002/ange.200602579).

One-pot, cis-selective synthesis of α-substituted β-trimethylsilyl-α,β-epoxyesters from α-ketoesters and diazo(trimethylsilyl)methylmagnesium bromide
Yoshiyuki Hari, Susumu Tsuchida, Toyohiko Aoyama*
Tetrahedron Lett. 2006, 47, 1977-1980 (doi:10.1016/j.tetlet.2006.01.067).

Efficient synthesis of o-alkynyl-N-pivaloylanilines from o-acyl-N-pivaloylanilines and lithium trimethylsilyldiazomethane
Yoshiyuki Hari, Tomoki Kanie, Toyohiko Aoyama*
Tetrahedron Lett. 2006, 47, 1137-1139 (doi:10.1016/j.tetlet.2005.12.051).

One-pot synthesis of 2,3-disubstituted N-tosylindoles from o-acyl-N-tosylanilines
Yoshiyuki Hari, Tomoki Kanie, Takashi Miyagi, Toyohiko Aoyama*
Synthesis 2006, 1249-1252 (doi:10.1055/s-2006-926398).

Synthesis and properties of 2’-O,4’-C-methyleneoxymethylene bridged nucleic acid
Yoshiyuki Hari, Satoshi Obika, Ryo Ohnishi, Ken Eguchi, Tomohisa Osaki, Hirofumi Ohishi, Takeshi Imanishi*
Bioorg. Med. Chem. 2006, 14, 1029-1038 (doi:10.1016/j.bmc.2005.09.020).

その他

アキラルリガンドの添加による不斉反応の改良
張 功幸
ファルマシア, 42, 470-471 (2006).

2005年

原著論文

New synthesis of t-butyl 1,2-dihydro-1-oxaazulene-3-carboxylates using lithium trimethylsilyldiazomethane
Susumu Tsuchida, Yoshiyuki Hari, Toyohiko Aoyama*
Heterocycles 2005, 65, 2667-2674 (doi:10.3987/COM-05-10504).

Facile, one-pot synthesis of bicyclic 2-pyridones from acyl isocyanates, N-phenylmaleimide and trimethylsilyldiazomethane
Yoshiyuki Hari, Tomoe Iguchi, Toyohiko Aoyama*
Synthesis 2005, 2147-2150 (doi:10.1055/s-2005-870002).

Synthesis and triplex-forming ability of 2’,4’-BNAs bearing imidazoles as a nucleobase
Yoshiyuki Hari, Satoshi Obika, Hiroyasu Inohara, Masahiro Ikejiri, Daisuke Une, Takeshi Imanishi*
Chem. Pharm. Bull. 2005, 53, 843-846 (doi:10.1248/cpb.53.843).

Regioselective synthesis of 1-arylindazoles via N-arylation of 3-trimethylsilylindazoles
Yoshiyuki Hari, Yoshimichi Shoji, Toyohiko Aoyama*
Tetrahedron Lett. 2005, 46, 3771-3774 (doi:10.1016/j.tetlet.2005.03.157).

Enantioselective addition of diethylzinc to aldehydes catalyzed by (1R,2R)-10-(dialkylamino)isoborneols
Yoshiyuki Hari, Toyohiko Aoyama*
Synthesis 2005, 583-587 (doi:10.1055/s-2005-861788).

2004年

原著論文

New synthesis of 3-substituted indoles using lithium trimethylsilyldiazomethane
Takashi Miyagi, Yoshiyuki Hari, Toyohiko Aoyama*
Tetrahedron Lett. 2004, 45, 6303-6305 (doi:10.1016/j.tetlet.2004.06.102).

Facile one-pot synthesis of di- and tri-substituted furans from acyl isocyanates using trimethylsilyldiazomethane
Yoshiyuki Hari, Tomoe Iguchi, Toyohiko Aoyama*
Synthesis 2004, 1359-1362 (doi:10.1055/s-2004-822397).

New synthesis of 3-substituted indazoles from 3-trimethylsilylindazole
Yoshiyuki Hari, Yoshimichi Shoji, Toyohiko Aoyama*
Synthesis 2004, 1183-1186 (doi:10.1055/s-2004-822351).

Facile synthesis of 3-trimethylsilylindazoles by [3+2]cycloaddition reaction of lithium trimethylsilyldiazomethane with benzynes
Yoshimichi Shoji, Yoshiyuki Hari, Toyohiko Aoyama*
Tetrahedron Lett. 2004, 45, 1769-1771 (doi:10.1016/j.tetlet.2003.12.086).

2003年

原著論文

New two-step synthesis of azulene-1-carboxylic esters using lithium trimethylsilyldiazomethane
Yoshiyuki Hari, Shunkichi Tanaka, Yasuta Takuma, Toyohiko Aoyama*
Synlett 2003, 2151-2154 (doi:10.1055/s-2003-42064).

Selective recognition of CG interruption by 2’,4’-BNA having 1-isoquinolone as a nucleobase in a pyrimidine motif triplex formation
Yoshiyuki Hari, Satoshi Obika, Mitsuaki Sekiguchi, Takeshi Imanishi*
Tetrahedron 2003, 59, 5123-5128 (doi:10.1016/S0040-4020(03)00728-2).

Synthesis and properties of a novel bridged nucleic acid with a P3’→N5’ phosphoramidate linkage, 5’-amino-2’,4’-BNA
Satoshi Obika, Osamu Nakagawa, Akiko Hiroto, Yoshiyuki Hari, Takeshi Imanishi*
Chem. Commun. 2003, 2202-2203 (doi:10.1039/B307290H).

Triplex formation involving 2’-O,4’-C-methylene bridged nucleic acid (2’,4’-BNA) with 1-isoquinolone base analogue: Efficient and selective recognition of C:G interruption
Hidetaka Torigoe*, Yoshiyuki Hari, Satoshi Obika, Takeshi Imanishi*
Nucleos. Nucleot. Nucleic Acids 2003, 22, 1571-1573 (doi:10.1081/NCN-120023036).

Triplex formation involving 2’-O,4’-C-methylene bridged nucleic acid (2’,4’-BNA) with 2-pyridone base analogue: Efficient and selective recognition of C:G interruption
Hidetaka Torigoe*, Yoshiyuki Hari, Satoshi Obika, Takeshi Imanishi*
Nucleos. Nucleot. Nucleic Acids 2003, 22, 1097-1099 (doi:10.1081/NCN-120022745).

その他

キラルジオキシランを用いたα,β-不飽和エステルの不斉エポキシ化反応
張 功幸
ファルマシア, 39, 447-448 (2003).

2002年

原著論文

Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: Strong sequence-specific recognition by 2’,4’-bridged nucleic acid containing 2-pyridones under physiological conditions
Satoshi Obika, Yoshiyuki Hari, Mitsuaki Sekiguchi, Takeshi Imanishi*
Chem. Eur. J. 2002, 8, 4796-4802 (doi:10.1002/1521-3765(20021018)8:20<4796::AID-CHEM4796>3.0.CO;2-O).

Synthesis and conformation of a novel bridged nucleoside with S-type sugar puckering, trans-3’,4’-BNA monomer
Satoshi Obika, Mitsuaki Sekiguchi, Tomohisa Osaki, Nao Shibata, Miyuki Masaki, Yoshiyuki Hari, Takeshi Imanishi*
Tetrahedron Lett. 2002, 43, 4365-4368 (doi:10.1016/S0040-4039(02)00784-0).

Effective synthesis of C-nucleosides with 2’,4’-BNA modification
Yoshiyuki Hari, Satoshi Obika, Minako Sakaki, Ken-ichiro Morio, Yuriko Yamagata, Takeshi Imanishi*
Tetrahedron 2002, 58, 3051-3063 (doi:10.1016/S0040-4020(02)00226-0).

Synthesis and conformation of 3’,4’-BNA monomers, 3’-O,4’-C-methyleneribonucleosides
Satoshi Obika, Ken-ichiro Morio, Daishu Nanbu, Yoshiyuki Hari, Hiromi Itoh, Takeshi Imanishi*
Tetrahedron 2002, 58, 3039-3049 (doi:10.1016/S0040-4020(02)00227-2).

その他

超機能性人工核酸の開発に向けて
今西 武，張 功幸
脳21, 5, 309-314 (2002).

2001年

原著論文

2’-O,4’-C-Methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: Thermodynamic and kinetic studies
Hidetaka Torigoe*, Yoshiyuki Hari, Mitsuaki Sekiguchi, Satoshi Obika, Takeshi Imanishi*
J. Biol. Chem. 2001, 276, 2354-2360 (doi:10.1074/jbc.M007783200).

A 2’,4’-bridged nucleic acid containing 2-pyridone as a nucleobase: Efficient recognition of a C･G interruption by triplex formation with a pyrimidine motif
Satoshi Obika, Yoshiyuki Hari, Mitsuaki Sekiguchi, Takeshi Imanishi*
Angew. Chem. Int. Ed. 2001, 40, 2079-2081 (doi:10.1002/1521-3773(20010601)40:11<2079::AID-ANIE2079>3.0.CO;2-Z).

2000年

原著論文

Triplex-forming enhancement with high sequence selectivity by single 2’-O,4’-C-methylene bridged nucleic acid (2’,4’-BNA) modification
Satoshi Obika, Yoshiyuki Hari, Tomomi Sugimoto, Mitsuaki Sekiguchi, Takeshi Imanishi*
Tetrahedron Lett. 2000, 41, 8923-8927 (doi:10.1016/S0040-4039(00)01607-5).

Triplex formation by an oligonucleotide containing conformationally locked C-nucleoside, 5-(2-O,4-C-methylene-β-D-ribofuranosyl)oxazole
Satoshi Obika, Yoshiyuki Hari, Ken-ichiro Morio, Takeshi Imanishi*
Tetrahedron Lett. 2000, 41, 221-224 (doi:10.1016/S0040-4039(99)02052-3).

Synthesis of conformationally locked C-nucleosides having a 2,5-dioxabicyclo[2.2.1]heptane ring system
Satoshi Obika, Yoshiyuki Hari, Ken-ichiro Morio, Takeshi Imanishi*
Tetrahedron Lett. 2000, 41, 215-219 (doi:10.1016/S0040-4039(99)01998-X).

1999年

原著論文

Preparation and properties of 2’,5’-linked oligonucleotide analogues containing 3’-O,4’-C-methyleneribonucleosides
Satoshi Obika, Ken-ichiro Morio, Yoshiyuki Hari, Takeshi Imanishi*
Bioorg. Med. Chem. Lett. 1999, 9, 515-518 (doi:10.1016/S0960-894X(99)00028-1).

Facile synthesis and conformation of 3’-O,4’-C-methyleneribonucleosides
Satoshi Obika, Ken-ichiro Morio, Yoshiyuki Hari, Takeshi Imanishi*
Chem. Commun. 1999, 2423-2424 (doi:0.1039/A907218G).

1998年

原著論文

Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2’-O,4’-C-methyleneribonucleosides
Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari, Jun-ichi Andoh, Ken-ichiro Morio, Takefumi Doi, Takeshi Imanishi*
Tetrahedron Lett. 1998, 39, 5401-5404 (doi:10.1016/S0040-4039(98)01084-3).

1997年

原著論文

Synthesis of 2’-O,4’-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C_3’-endo sugar puckering
Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari, Ken-ichiro Morio, Yasuko In, Toshimasa Ishida, Takeshi Imanishi*
Tetrahedron Lett. 1997, 38, 8735-8738 (doi:10.1016/S0040-4039(97)10322-7).