2021年

原著論文

Artificial Host Molecules to Covalently Capture 8‑Nitro-cGMP inNeutral Aqueous Solutions and in Cells
Yasufumi Fuchi,Hirotaka Murase, Ryosuke Kai, Kakeru Kurata, Satoru Karasawa, Shigeki Sasaki*
Bioconjugate Chem. 2021, 32, 385-393 (doi:10.1021/acs.bioconjchem.1c00012).

Push–Pull Bisnaphthyridylamine Supramolecular Nanoparticles: Polarity‐Induced Aggregation‐ and Crystallization‐Induced Emission Enhancement and Fluorescence Resonance Energy Transfer
Ryusuke Hagihara, Tomohiro Umeno, Shoji Ueki, Daisuke Yoshihara, Yasufumi Fuchi, Kazuteru Usui, Masaomi Sakuma, Ken-ichi Yamada, Satoru Karasawa*
Chem. Eur. J. 2021, 27, 3039-3046 (doi:10.1002/chem.202003854).

2020年

原著論文

Characterization of Push–Pull-Type Benzo[X]quinoline Derivatives (X = g or f): Environmentally Responsive Fluorescent Dyes with Multiple Functions
Yasufumi Fuchi,* Tomohiro Umeno, Yuichiro Abe, Keita Ikeno, Ryu Yamasaki, Iwao Okamoto, Kazuteru Usui,* Satoru Karasawa*
J. Org. Chem. 2020, 85, 13177–13190 (doi:10.1021/acs.joc.0c01878). (Supplementary Cover).

A fully synthetic 6-aza-artemisinin bearing an amphiphilic chain generates aggregates and exhibits anti-cancer activities
Hikari Koi, Norihito Takahashi, Yasufumi Fuchi, Tomohiro Umeno, Yukiko Muramatsu, Hiroyuki Seimiya, Satoru Karasawa*, Hiroki Oguri*
Org. Biomol. Chem. 2020, 18, 5339-5343.

Characterization and Water-Proton Longitudinal Relaxivities of Liposome-Type Radical Nanoparticles Prepared via a Supramolecular Approach
Ryoma Shiraishi, Shota Matsumoto, Yasufumi Fuchi, Tatsuya Naganuma, Daisuke Yoshihara, Kazuteru Usui, Ken-ichi Yamada, Satoru Karasawa*
Langmuir 2020, 36, 5280–5286.

2019年

原著論文

Effects of substituents on the properties of metal-free MRI contrast agents
Shigeki Kobayashi, Yasufumi Fuchi, Yuta Matsuoka, Go Hirai, Ken-ichi Yamada, Satoru Karasawa*
ACS. Omega 2019, 4, 20715-20723 (doi: 10.1021/acsomega.9b03003).

Selective synthesis of substituted amino-quinoline derivatives by C-H activation and fluorescence evaluation of their lipophilicity- responsive properties
Yasufumi Fuchi*, Masaomi Sakuma, Kohei Ohyama, Ryusuke Hagihara, Minaki Kohno, Koichi Hamada, Akihiro Mizutani, Satoru Karasawa*
Sci. Rep. 2019, 9:17723, 1-9 (doi: 10.1038/s41598-019-53882-z).

Photophysical properties of emissive pyrido[3,2-c]carbazole derivatives and apoptosis induction: Development towards theranostic
Masaomi Sakuma, Yasufumi Fuchi*, Kazuteru Usui, Satoru Karasawa*
Chem. Asian. J. 2019, 14, 3938-3945 (doi: 10.1002/asia.201901200).

Fluorescence properties and exciplex formation of emissive naphthyridine derivatives: Application as sensors for amines
Junko Hirota, KazuteruUsui, YasufumiFuchi, Masaomi Sakuma, Shota Matsumoto, Ryusuke Hagihara, Satoru Karasawa*
Chem. Eur. J. 2019, 25, 14943-14952 (doi: 10.1002/chem.201903643).

Development of turn-on probes for acids triggered by aromaticity enhancement using tricyclic amidine derivatives
Shota Matsumoto, Yasufumi Fuchi, Kazuteru Usui, Go Hirai, Satoru Karasawa*
J. Org. Chem. 2019, 84, 6612-6622 (doi: 10.1021/acs.joc.9b00023).

その他

近赤外発光団を導入した蛍光プローブによる生理活性化合物の探索
渕　靖史
ぶんせき 2019, 524.

2018年

原著論文

Fluorescence tumor-imaging using a thermo-responsive molecule with an emissive aminoquinoline derivatives
Takeru Araki, Yasufumi Fuchi, Shuhei Murayama, Ryoma Shiraishi, Tokimi Oyama, Mariko Aso, Ichio Aoki, Shigeki Kobayashi, Ken-ichi Yamada, Satoru Karasawa*
Nanomaterials 2018, 8, 782 (doi: 10.3390/nano8100782).

Self-assembled biradical ureabenzene nanoparticles for magnetic resonance imaging
Kosuke Morishita, Shoji Ueki, Yasufumi Fuchi, Shuhei Murayama, Tomoyo Kaneko, Nozomi Narita, Shigeki Kobayashi, Go Hirai, Ichi Aoki, Satoru Karasawa*
ACS Appl. Nano Mater. 2018, 1, 6967-6975 (doi: 10.1021/acsanm.8b01774).

Effect of hydrophobicity on the self-assembly behavior of urea benzene derivatives in aqueous solution
Yuna Okamoto, Kosuke Morishita, Yasufumi Fuchi, Shigeki Kobayashi, Satoru Karasawa*
Appl. Sci. 2018, 8, 1080 (doi: 10.3390/app8071080).

Luminescent europium sensors for specific detection of 8-oxo-dGTP by time-gated fluorescence
Yasufumi Fuchi, Takashi Fukuda, Shigeki Sasaki*
Bioorg. Med. Chem. 2018, 26, 3254-3260 (doi: 10.1016/j.bmc.2018.04.052).

2016年

原著論文

Synthetic receptor molecules for selective fluorescent detection of 8-oxo-dGTP in aqueous media
Yasufumi Fuchi, Takashi Fukuda, Shigeki Sasaki*
Org. Biomol. Chem. 2016, 14, 7949-7955 (doi: 10.1039/C6OB01485B).

その他

化学反応性を獲得した核酸－酸化的に化学修飾されたグアノシン誘導体
渕　靖史
月刊化学 2016, 71, 70-71.

2015年

原著論文

New nitroG-Grasp molecules with enhanced capture reactivity for 8-nitroguanosine in the aqueous media
Yasufumi Fuchi, Shigeki Sasaki*
Chem. Pharm. Bull. 2015, 63, 913-919 (doi: 10.1248/cpb.c15-00550).

Development of new 1,3-diazaphenoxazine derivatives (ThioG-Grasp) to covalently capture 8-thioguanosine
Yasufumi Fuchi, Hideto Ohbayashi, Shigeki Sasaki*
Molecules 2015, 20, 1078-1087 (doi: 10.3390/molecules20011078).

2014年

原著論文

Efficient covalent capture of 8-nitroguanosine via a multiple hydrogen-bonded
Yasufumi Fuchi, Shigeki Sasaki*
Org. Lett. 2014, 16, 1760-1763 (doi: 10.1021/ol500452r).

2011年

原著論文

Optimization of fluorescence property of the 8-oxodGclamp derivative for better selectivity for 8-oxo-2'-deoxyguanosine
Yohei Koga, Yasufumi Fuchi, Osamu Nakagawa, Shigeki Sasaki*
Tetrahedron 2011, 67, 6746-6752 (doi: 10.1016/j/.tet.2011.03.111).

2010年

原著論文

Novel benzofurans with ^99mTc complexes as probes for imaging cerebral β-amyloid plaques
Masahiro Ono, Yasufumi Fuchi, Takeshi Fuchigami, Nobuya Kobashi, Hiroyuki Kimura, Mamoru Haratake, Hideo Saji, Morio Nakayama
ACS Med. Chem. Lett. 2010, 1, 443–447 (doi: 10.1021/ml100140d).