原著論文

2022

 1.Base-induced isomerization of red uroleuconaphins revisited: Characterization and absolute stereochemistry of the yellow aphid pigments uroleuconaphins A2 and B2
Chiharu Ozakai, Kei Kitamura, Mitsuyo Horikawa, Tetsuto Tsunoda, Hiroto Kaku
New J. Chem., 2022, 46, 16256-16259. DOI:10.1039/D2NJ02676G Advance Article に選ばれました!!front coverに選ばれました!!

 2.Strong acid-promoted skeletal remodeling of the aphid pigment: red uroleuconaphin to green viridaphin
Chiharu Ozakai, Kei Kitamura, Mitsuyo Horikawa, To-sho Hoshiyama, Akari Imamura, Tatsuro Yoneyama, Akemi Umeyama, Masaaki Noji, Tetsuto Tsunoda, Hiroto Kaku
New J. Chem., 2022, 46, 2600-2604. DOI:10.1039/D1NJ05261F back coverに選ばれました!!


2021

 1.Synthesis of the Common Monomeric Unit of Uroleuconaphins and Viridaphins via Hauser–Kraus Annulation
Kei Kitamura, Hinano Kanagawa, Chiharu Ozakai, Taichi Nishimura, Hayato Tokuda, Tetsuto Tsunoda, Hiroto Kaku
SYNTHESIS, 2021, 53 (9), 1629-1635. DOI:10.1055/a-1334-6982


2020

 1.Total Syntheses and Cytotoxic Evaluations of Cryptolactones A1, A2, B1, B2, and Their Derivatives
Makoto Inai, Yoki Oguri, Mitsuyo Horikawa, Hiroto Kaku, Shinya Suzuki, Kei Kitamura, Tetsuto Tsunoda
Chem. Pharm. Bull., 2020, 68 (4), 380-383. DOI:10.1248/cpb.c19-01114 Featured Articleに選ばれました!!


2019

 1.Piperidine and Azetidine Formation by Direct Cyclization of Diols with N-Nonsubstituted Sulfonamide under the Mitsunobu Conditions Utilizing (Cyanomethylene)tributylphosphorane (CMBP) and Its Application to the Synthesis of Lupinine
Hiroto Kaku, Yuhei Sonoda, Hideyuki Hishida, Yuri Taniguchi, Akiko Kubo, Takumi Hamaguchi, Mitsuyo Horikawa, Makoto Inai, Kei Kitamura, Tetsuto Tsunoda
HETEROCYCLES, 2019, 98 (11), 1525-1535. DOI:10.3987/COM-19-14171


2018

 1.Optically Active 2,7,10,15-Tetrahydroxytetraphenylene: Clathrates with Both Enantiomers of 1-Phenylethylamine and Their Stability
Hiroto Kaku, Akinobu Mitarai, Natsuko Okamoto, Kenta Tanaka, Sayaka Ichikawa, Takahiro Yamamoto, Makoto Inai, Takeshi Nishii, Mitsuyo Horikawa, Tetsuto Tsunoda
Eur. J. Org. Chem., 2018, 48, 6991-6999. DOI:ejoc.201801422

 2.A role of uroleuconaphins, polyketide red pigments in aphid, as a chemopreventor in the host defense system against infection with entomopathogenic fungi
Mitsuyo Horikawa, Mitsuaki Shimazu, Maki Aibe, Hiroto Kaku, Makoto Inai, Tetsuto Tsunoda
J. Antibiotics, 2018, 71, 992–999. DOI:10.1038/s41429-018-0093-4

 3.3,3-Dimethoxypropylsulfonyl Group: A new versatile protecting and activating group for amine synthesis
Izumi Sakamoto, Kazuya Iwaoka, Yuta Kawada, Takanori Naito, Kazuyoshi Makida, Yuki Takeuchi, Takeshi Nishii, Mitsuyo Horikawa, Hiroto Kaku, Tetsuto Tsunoda
Tetrahedron, 2018, 74 (24), 3052-3060. DOI:10.1016/j.tet.2018.04.088

 4.Deracemization of α-monosubstituted cyclopentanones in the presence of a TADDOL-type host molecule
Hiroto Kaku, Minami Ito, Mitsuyo Horikawa, Tetsuto Tsunoda
Tetrahedron, 2018, 74 (4), 124-129. DOI:10.1016/j.tet.2017.11.045

総説・その他

2022


2021


2020


2019