略歴
2009年3月 徳島文理大学 香川薬学部 創薬学科 卒業 学士(薬学)
2009年9月 薬剤師免許取得
2011年3月 徳島文理大学大学院 香川薬学研究科 創薬科学専攻 博士前期課程 修了 修士(薬学)
2013年4月 日本学術振興会 特別研究員
2014年3月 徳島文理大学大学院 香川薬学研究科 創薬科学専攻 博士後期課程 修了 博士(薬学)
2015年4月 株式会社テクノプロ テクノプロ・R&D社 住友化学 筑波開発研究所勤務
2016年4月 徳島文理大学 香川薬学部 助教
2022年4月 徳島文理大学 薬学部 助教
専門分野
核酸化学
所属学会
日本薬学会
日本化学会
日本光医学・光生物学会
日本分子生物学会
日本環境変異原学会会員
担当授業
物理学実習2
研究内容
損傷塩基修復酵素hOGG1による塩基除去反応機能の研究
業績一覧
Yoshiyuki Tanaka,* Daichi Yamanaka, Saori Morioka, Taishi Yamaguchi, Masayuki Morikawa, Takashi S. Kodama, Vladimír Sychrovský, Chojiro Kojima, Yoshikazu Hattori, Physicochemical characterization of the catalytic unit of hammerhead ribozyme and its relationship with the catalytic activity. Biophysica (MDPI), (2022) in press. DOI: 10.3390/xxxxx
Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima, Hiroshi Miyazawa, Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases. Genes and Environment, (2022) 44(1) 7. DOI: 10.1186/s41021-022-00236-3
Katsuhito Kino, Takayuki Ohshima, Hajime Takeuchi, Takanobu Kobayashi, Taishu Kawada, Masayuki Morikawa, Hiroshi Miyazawa, Considering Existing Factors That May Cause Radiation Hormesis at <100 mSv and Obey the Linear No-Threshold Theory at ≥100 mSv. Challenges, (2021) 12(2) 33. DOI: 10.3390/challe12020033
Katsuhito Kino, Taishu Kawada, Masayo Hirao-Suzuki, Masayuki Morikawa, Hiroshi Miyazawa, Products of Oxidative Guanine Damage Form Base Pairs with Guanine. Intternational journal of Molecular Science, (2020) 21(20) 7645. DOI: 10.3390/ijms21207645
Toshie Fujishima, Takuro Komatsu, Yuri Takao, Wataru Yonamine, Tsutomu Suenaga, Hiroaki Isono, Masayuki Morikawa, Keisuke Takaguchi, Design and concise synthesis of novel vitamin D analogues bearing a functionalized aromatic ring on the side chain. Tetrahedron, (2019) 75(8) 1098-1106. DOI: 10.1016/j.tet.2019.01.019
Katsuhito Kino, Masayo Hirao-Suzuki, Masayuki Morikawa, Akane Sakaga, Hiroshi Miyazawa, Generation, repair and replication of guanine oxidation products. Genes and environment, (2017) 39(21) 1-8. DOI: 10.1186/s41021-017-0081-0
Masayo Suzuki, Katsuhito Kino, Taishu Kawada, Takanori Oyoshi, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Contiguous 2,2,4-triamino-5(2H)-oxazolone obstructs DNA synthesis by DNA polymerases α, β, η, ι, κ, REV1 and Klenow Fragment exo-, but not by DNA polymerase ζ. Journal of biochemistry, (2016) 159(3) 323-329. DOI: 10.1093/jb/mvv103
喜納 克仁, 鈴木 雅代, 森川 雅行, グアニンの1電子酸化反応. 放射線生物研究, (2015) 50(4) 305-320. CiNii Articles
Kentaro Takahama, Arisa Miyawaki, Takumi Shitara, Keita Mitsuya, Masayuki Morikawa, Masaki Hagihara, Katsuhito Kino, Ayumu Yamamoto, Takanori Oyoshi, G-Quadruplex DNA- and RNA-Specific-Binding Proteins Engineered from the RGG Domain of TLS/FUS. ACS chemical biology, (2015) 10(11) 2564-2569. DOI: 10.1021/acschembio.5b00566
Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, Calculation of the HOMO localization of Tetrahymena and Oxytricha telomeric quadruplex DNA. Bioorganic & Medicinal Chemistry Letters, (2015) 25(16) 3359-3362. DOI: 10.1016/j.bmcl.2015.05.050
Masayo Suzuki, Katsuhito Kino, Taishu Kawada, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Analysis of Nucleotide Insertion Opposite 2,2,4-Triamino-5(2H)-oxazolone by Eukaryotic B- and Y-Family DNA Polymerases. Chemical research in toxicology, (2015) 28(6) 1307-1316. DOI: 10.1021/acs.chemrestox.5b00114
Takanobu Kobayashi, Masayo Suzuki, Masayuki Morikawa, Katsuhito Kino, Sei-ichi Tanuma, Hiroshi Miyazawa, Transcriptional Regulation of Tal2 Gene by All-trans Retinoic Acid (atRA) in P19 Cells. Biological and pharmaceutical bulletin, (2015) 38(2) 248-256. DOI: 10.1248/bpb.b14-00617
Katsuhito Kino, Masayo Suzuki, Masayuki Morikawa, Takanobu Kobayashi, Shigenori Iwai, Hiroshi Miyazawa, Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and v have incision activity on 2,2,4-triamino- 5(2H)-oxazolone. Genes and environment, (2015) 37(1) 1-6. DOI: 10.1186/s41021-015-0022-8
Masayo Suzuki, Kazuya Ohtsuki, Katsuhito Kino, Teruhiko Kobayashi, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Effects of stability of base pairs containing an oxazolone on DNA elongation. Journal of nucleic acids, (2014) 2014 1-9. DOI: 10.1155/2014/178350
Masayuki Morikawa, Katsuhito Kino, Eriko Asada, Kosuke Katagiri, Kanami Mori-Yasumoto, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide. Molbank, (2014) 2014(4) 1-5. DOI: 10.3390/M836
Masayo Suzuki, Katsuhito Kino, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Calculating Distortions of Short DNA Duplexes with Base Pairing Between an Oxidatively Damaged Guanine and a Guanine. Molecules, (2014) 19(8) 11030-11044. DOI: 10.3390/molecules190811030
Masayuki Morikawa, Katsuhito Kino, Takeshi Senda, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, Formation of a Flavin-Linked Peptide. Molecules, (2014) 19(7) 9552-9561. DOI: 10.3390/molecules19079552
Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, Analysis of guanine oxidation products in double-stranded DNA and proposed guanine oxidation pathways in single-stranded, double-stranded or quadruplex DNA. Biomolecules, (2014) 4(1) 140-159. DOI: 10.3390/biom4010140
Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashia, Hiroshi Miyazawa, Product analysis of photooxidation in isolated quadruplex DNA; 8-oxo-7,8-dihydroguanine and its oxidation product at 3’-G are formed instead of 2,5- diamino-4H-imidazol-4-one. RSC advances, (2013) 3(48) 25694-25697. DOI: 10.1039/c3ra44290j
Masayo Suzuki, Katsuhito Kino, Masayuki Morikawa, Takanobu Kobayashi, Rie Komori, Hiroshi Miyazawa, Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine. Molecules, (2012) 17(6) 6705-6715. DOI: 10.3390/molecules17066705
森川 雅行, 喜納 克仁, 宮澤 宏, DNA損傷の発生と細胞への影響に関する化学的視点. 放射線生物研究, (2010) 45(3) 268-285. DOI: CiNii Articles
Masayuki Morikawa, Katsuhito Kino, Masayo Suzuki, Takanobu Kobayashi, Rie Komori, Hiroshi Miyazawa, Iodine: Characteristics, Sources and Health Implications Chapter 7.1 "Oxidation of 8-oxoguanine with iodine and proposed mechanisms." (Biochemistry Research Trends: Chemical Engineering Methods and Technology). (2012) Nova Biomedical Books. ISBN:1619427087.
Katsuhito Kino, Masayuki Morikawa, Teruhiko Kobayashi, Takanobu Kobayashi, Rie Komori, Yoshihisa Sei, Hiroshi Miyazawa, The oxidation of 8-oxo-7,8-dihydroguanine by iodine. Bioorganic & medicinal chemistry letters, (2010) 20(12) 3818-3820. DOI: 10.1016/j.bmcl.2010.04.032
Masayuki Morikawa, Teruhiko Kobayashi, Takanobu Kobayashi, Rie Komori, Yoshihisa Sei, Hiroshi Miyazawa, Katsuhito Kino, The oxidation of 2′-deoxy-8-oxoguanosine by iodine. Nucleic acids symposium series, (2004) 53(1) 219-220. DOI: 10.1093/nass/nrp110