業績

Yoshiyuki Tanaka,* Daichi Yamanaka, Saori Morioka, Taishi Yamaguchi, Masayuki Morikawa, Takashi S. Kodama, Vladimír Sychrovský, Chojiro Kojima and Yoshikazu Hattori, Physicochemical characterization of the catalytic unit of hammerhead ribozyme and its relationship with the catalytic activity. Biophysica (MDPI), 2, 221-239 (2022). (DOI: 10.3390/biophysica2030022)

Noriko Saito Tarashima, Yusuke Kumanomido, Katsuyuki Nakashima, Yoshiyuki Tanaka and Noriaki Minakawa,* Synthesis of a cyclic dinucleotide analog with ambiguous bases, 5-aminoimidazole-4-carboxamide. The Journal of Organic Chemistry, 86, 15004-15010 (2021). DOI: 10.1021/acs.joc.1c01706

Takenori Dairaku,* Rika Kawai, Kanako Nozawa-Kumada, Kentaro Yoshida, Tetsuya Ono, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka, and Yoshitomo Kashiwagi,* Chemical reduction of Ag⁺ to Ag employing organic electron donors: Evaluation of the effect of Ag⁺-mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles. Dalton Transactions, 50, 12208-12214 (2021). DOI: 10.1039/d1dt01927a

Takenori Dairaku,* Rika Kawai, Teppei Kanaba, Tetsuya Ono, Kentaro Yoshida, Hajime Sato, Kanako Nozawa-Kumada, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka* and Yoshitomo Kashiwagi,* Effect of cytosine–Ag⁺–cytosine base pairing on the redox potential of the Ag⁺/Ag couple and the chemical reduction of Ag⁺ to Ag by tetrathiafulvalene. Dalton Transactions, 50, 7633-7639 (2021). DOI: 10.1039/d1dt00975c

Ryo Yamada,* Issei Nomura, Yuki Yamaguchi, Yosuke Matsuda, Yoshikazu Hattori, Hirokazu Tada, Akira Ono and Yoshiyuki Tanaka,* Electrical conductance measurement of HgII- mediated DNA duplex in buffered aqueous solution. Nucleosides, Nucleotides & Nucleic Acids, 39, 1083-1087 (2020). DOI: 10.1080/15257770.2020.1755044

Filip Šebesta, Jakub Šebera, Vladimír Sychrovský, Yoshiyuki Tanaka and Jaroslav V. Burda,* QM and QM/MM umbrella sampling MD study of the formation of Hg(II)–thymine bond: Model for evaluation of the reaction energy profiles in solutions with constant pH. Journal of Computational Chemistry, 41, 1509-1520 (2020). DOI: 10.1002/jcc.26194

Mitsuhiro Yamada and Yoshiyuki Tanaka*, Structure–activity relationship of pseudoknot-type hammerhead ribozyme reveals key structural elements for enhanced catalytic activity. Nucleosides, Nucleotides & Nucleic Acids, 39, 245-257 (2020). DOI: 10.1080/15257770.2019.1669169

Naohiro Kobayashi*, Yoshikazu Hattori, Takashi Nagata, Shoko Shinya, Peter Güntert, Chojiro Kojima, and Toshimichi Fujiwara, Noise peak filtering in multi-dimensional NMR spectra using convolutional neural networks, Bioinformatics 34, 4300–4301 (2018). DOI: bioinformatics/bty581

Yoshikazu Hattori, Daichi Yamanaka, Saori Morioka, Taishi Yamaguchi, Honoka Tomonari, Chojiro Kojima, and Yoshiyuki Tanaka*, NMR spectroscopic characterization of a model RNA duplex reflecting the core sequence of hammerhead ribozymes, Nucleosides, Nucleotides & Nucleic Acids 37, 383–396 (2018). DOI: 10.1080/15257770.2018.1473877

Masakazu Sono*, Hitomi Yamaguchi, Katsuyuki Nakashima, and Motoo Tori, A New Diterpenoid and a Lignan from Pinus thunbergii, Natural Product Communications 12, 1181-1184 (2017).

Yoshinori Saito*, Motoki Hidaka, Akané Fukuda, Yasuko Okamoto*, Katsuyuki Nakashima, Motoo Tori, Ryo Hanai*, Xun Gong*, Eiji Watanabe, and Chiaki Kuroda*, Intra-specific diversity of the chemical composition of Ligularia lamarum in the Hengduan Mountains, China: The structures of four new eremophilanes and a new seco-eremophilane, Phytochemistry Letters 20, 139–145 (2017). DOI: 10.1016/j.phytol.2017.04.026

Yoshikazu Hattori, David Heidenreich, Yuki Ono, Toshihiko Sugiki, Kei‑ichi Yokoyama, Ei‑ichiro Suzuki, Toshimichi Fujiwara, and Chojiro Kojima*, Protein 19F-labeling using transglutaminase for the NMR study of intermolecular interactions, Journal of Biomolecular NMR 68, 271–279 (2017). DOI: 10.1007/s10858-017-0125-6

Jiro Kondo*, Yoshinari Tada, Takenori Dairaku, Yoshikazu Hattori, Hisao Saneyoshi, Akira Ono, and Yoshiyuki Tanaka, A metallo-DNA nanowire with uninterrupted one-dimensional silver array, Nature Chemistry 9, 956–960 (2017). DOI: 10.1038/nchem.2808
プレスリリースPDF (上智大)　Highlight (ChemBioChem)　News and Views (Nature Chemistry)

Jakub Šebera, Yoshikazu Hattori, Daichi Sato, David Řeha, Radim Nencka, Takashi Kohno, Chojiro Kojima*, Yoshiyuki Tanaka*, and Vladimír Sychrovský*, The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine, Nucleic Acids Research 45, 5231-5242 (2017). DOI: 10.1093/nar/gkx157

Kazuki Ishii, Noriko Saito-Tarashima, Masashi Ota, Seigi Yamamoto, Yasuko Okamoto, Yoshiyuki Tanaka, and Noriaki Minakawa*, Practical synthesis of 4'-selenopurine nucleosides by combining chlorinated purines and 'armed' 4-selenosugar, Tetrahedron 72, 6589-6594 (2016). DOI: 10.1016/j.tet.2016.08.071

Katsuyuki Nakashima, Hatsuna Matsunaga, Masako Ito, Hiroshi Minami, Akihito Aiba, Norihiro Fujisaki, and Motoo Tori, Macrocyclization Using RCM Reactions. Synthesis of Simple Metacyclophanes and Synthetic Efforts Toward Platycarynol, a 15-Membered Aromatic Ether, Natural Product Communications 11, 1135-1142 (2016).

Takenori Dairaku*, Kyoko Furuita, Hajime Sato, Jakub Šebera, Katsuyuki Nakashima, Jiro Kondo, Daichi Yamanaka, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Vladimír Sychrovský*, Chojiro Kojima*, and Yoshiyuki Tanaka*, Structure Determination of an AgI-Mediated Cytosine–Cytosine Base Pair within DNA Duplex in Solution with 1H/15N/109Ag NMR Spectroscopy, Chemistry A Europian Journal 22, 13028–13031 (2016). DOI: 10.1002/chem.201603048

Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Šebera, Katsuyuki Nakashima, Akira Ono, Vladimír Sychrovský, Chojiro Kojima, and Yoshiyuki Tanaka*, Hg II /Ag I-mediated base pairs and their NMR spectroscopic studies, Inorganica Chimica Acta 452, 34-42 (2016). DOI: 10.1016/j.ica.2016.03.018

Jakub Šebera, Yoshiyuki Tanaka, Akira Ono, and Vladimír Sychrovský*, The effect of chemical modification of DNA base on binding of Hg II and Ag I in metal-mediated base pairs, Inorganica Chimica Acta 452, 199-204 (2016). DOI: 10.1016/j.ica.2016.03.007

Yasuko Okamoto, Mizuho Taniguchi, Katsuyuki Nakashima, Xun Gong, Ryo Hanai, Chiaki Kuroda, and Motoo Tori, Chemical Constituents of Ligularia wilsoniana Collected in Chongqing, China, Natural Product Communications 11, 149-152 (2016).

Yasuko Okamoto, Mizuho Taniguchi, Kaori Terada, Katsuyuki Nakashima, Xun Gong, Ryo Hanai, Motoo Tori, and Chiaki Kuroda, Diversity in Chemical Constituents of Ligularia longihastata Collected in China, Natural Product Communications 11, 145-148 (2016).

Martin Dracinsky, Michal Sala, Blanka Klepetarova, Jakub Šebera, Jiri Fukal, Veronika Holeckova, Yoshiyuki Tanaka, Radim Nencka, and Vladimír Sychrovský*, Benchmark Theoretical and Experimental Study on 15N NMR Shifts of Oxidatively Damaged Guanine, The Journal of Physical Chemistry B 120, 915-925 (2016). DOI: 10.1021/acs.jpcb.5b11428

Yoshinori Saito, Saori Iga, Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong*, Chiaki Kuroda*, and Motoo Tori*, Terpenoids from Ligularia virgaurea collected in China: the first example of two bakkane derivatives with an anhydride-type ring C and nineteen new chemical constituents, Tetrahedron 44, 8428-8435 (2015). DOI: 10.1016/j.tet.2015.09.011

Yoshiyuki Tanaka*, Jiro Kondo, Vladimír Sychrovský, Jakub Šebera, Takenori Dairaku, Hisao Saneyoshi, Hidehito Urata, Hidetaka Torigoe, and Akira Ono*, Structures, physicochemical properties, and applications of T-Hg II-T, C-Ag I-C, and other metallo-base-pairs, Chemical Communications 51, 17343-17360 (2015). DOI: 10.1039/C5CC02693H

Jiro Kondo*, Yoshinari Tada, Takenori Dairaku, Hisao Saneyoshi, Itaru Okamoto, Yoshiyuki Tanaka, and Akira Ono, High-resolution Crystal Structure of Silver(I)-RNA Hybrid Duplex Containing Watson-Crick-like C-Silver(I)-C Metallo-Base Pairs, Angewandte Chemie International Edition 54, 13323-13326 (2015).. DOI: 10.1002/anie.201507894

Takenori Dairaku, Kyoko Furuita, Hajime Sato, Yoshinori Kondo, Chojiro Kojima, Akira Ono, and Yoshiyuki Tanaka*, Exploring a DNA Sequence for the Three-Dimensional Structure Determination of a Silver(I)-Mediated C-C Base Pair in a DNA Duplex by 1H NMR Spectroscopy, Nucleosides, Nucleotides & Nucleic Acids 34, 877-900 (2015). DOI: 10.1080/15257770.2015.1088160

Katsuyuki Nakashima, Hiroyuki Kawano, Minako Kumano, Hikari Kodama, Masayo Kameoka, Akiyo Yamamoto, Reiko Mizutani, Masakazu Sono, and Motoo Tori*, What is the absolute configuration of (+)-crispatanolide isolated from Makinoa crispata (liverwort)? Tetrahedron Letters 56, 49112-4915 (2015). DOI: 10.1016/j.tetlet.2015.06.083

Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Šebera, Daichi Yamanaka, Hiroyuki Otaki, Shoko Kikkawa, Yoshinori Kondo, Ritsuko Katahira, F. Matthias Bickelhaupt, Celia Fonseca Guerra, Akira Ono, Vladimír Sychrovský*, Chojiro Kojima*, and Yoshiyuki Tanaka*, Direct detection of the mercury-nitrogen bond in the thymine-Hg II-thymine base-pair with 199Hg NMR spectroscopy, Chemical Communications 51, 8488-8491 (2015). DOI: 10.1039/c5cc02423d

Yoshinori Saito, Takanori Otsubo, Yuko Iwamoto,Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong, Chiaki Kuroda, and Motoo Tori, Four New Sesquiterpenoids from Ligularia subspicata Collected in China; Isolation of a Bakkane-type Lactone, an Eremophilane-type Lactone, and Two Ortho Esters, Natural Product Communications 10, 831-833 (2015).

Mizuho Taniguchi, Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong, Chiaki Kuroda, and Motoo Tori, Constituents of Ligularia brassicoides Collected in China: A New Diels-Alder Adduct of Eremophilan-10β-ol and Methacrylic Acid, Natural Product Communications 10, 827-830 (2015).,

Katsuyuki Nakashima, Yuzuru Kondo, Kosei Yoshimasu, Masakazu Sono, and Motoo Tori, Synthesis of chiral hexasubstituted cyclohexanediol, a key intermediate for the synthesis of verticillol, from (+)-dihydrocarvone; attempted cyclization to 12-membered carbocycle in verticillol using RCM reaction, Natural Product Communications 10, 551-555 (2015).

Saori Kataoka, Kyoko Furuita, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, and Chojiro Kojima, 1H, 15N and 13C resonance assignments of the conserved region in the middle domain of S. pombe Sin1 protein, Biomolecular NMR Assignment 9, 89-92 (2015). DOI: 10.1007/s12104-014-9550-6

Kyoko Furuita, Saori Kataoka, Toshihiko Sugiki, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, and Chojiro Kojima, Utilization of paramagnetic relaxation enhancements for high-resolution NMR structure determination of a soluble loop-rich protein with sparse NOE distance restraints, Journal of Biomolecular NMR 61, 55-64 (2015). DOI: 10.1007/s10858-014-9882-7

Jakub Šebera, Lukáš Trantírek, Yoshiyuki Tanaka, Radim Nencka, Jiří Fukal, and Vladimír Sychrovský, The activation of N-glycosidic bond cleavage operated by base-excision repair enzyme hOGG1; theoretical study of the role of Lys 249 residue in activation of G, OxoG and FapyG, RSC Advances 4, 44043-44051 (2014). DOI: 10.1039/C4RA08278H

Mituhiro Kuriyama, Yoshinori Kondo, and Yoshiyuki Tanaka, Pseudoknot interaction-mediated activation of type I hammerhead ribozyme: A new class of gene-therapeutic agents, Nucleosides, Nucleotides & Nucleic Acids 33, 466-480 (2014). DOI: 10.1080/15257770.2014.887098

Mituhiro Kuriyama, Kaichiro Haruta, Takenori Dairaku, Takuya Kawamura, Shoko Kikkawa, Kiyofumi Inamoto, Hirokazu Tsukamoto, Yoshinori Kondo, Hidetaka Torigoe, Itaru Okamoto, Akira Ono, Eugene H. Morita, and Yoshiyuki Tanaka, Hg2+ -trapping Beads: Hg2+ -specific Recognition through Thymine-Hg(II)-Thymine Base Pairing, Chemical Pharmaceutical Bulletin 62, 709-712 (2014). DOI: 10.1248/cpb.c13-00918

Jakub Šebera, Lukáš Trantirek, Jiří Fukal, Yoshiyuki Tanaka, and Vladimír Sychrovský, Mechanism of base excision with the hOGG1 DNA repair enzyme Chemicke Listy 108, 364-367 (2014).

Irena Kratochvílová, Martin Golan, Martin Vala, Miroslava Špérová, Martin Weiter, Ondrej Páv, Jakub Šebera, Ivan Rosenberg, Vladimír Sychrovský, Yoshiyuki Tanaka, and F. Matthias Bickelhaupt, Theoretical and Experimental Study of Charge Transfer through DNA: Impact of Mercury Mediated T-Hg-T Base Pair, The Journal of Physical Chemistry B 118, 5374-5381 (2014).. DOI: 10.1021/jp501986a

Jiro Kondo, Tom Yamada, Chika Hirose, Itaru Okamoto, Yoshiyuki Tanaka, and Akira Ono, Crystal Structure of Metallo-DNA Duplex Containing Consecutive Watson-Crick-like T-Hg(II)-T Base Pairs, Angewandte Chemie International Edition 53, 2385-2388 (2014). DOI: 10.1002/anie.201309066

Hiroshi Yamaguchi, Jakub Šebera, Jiro Kondo, Shuji Oda, Tomoyuki Komuro, Takuya Kawamura, Takenori Daraku, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Jaroslav V. Burda, Chojiro Kojima, Vladimír Sychrovský, and Yoshiyuki Tanaka, The structure of metallo-DNA with consecutive T-HgII-T base-pairs explains positive entropy for the metallo-base-pair formation, Nucleic Acids Research 42, 4094-4099 (2014). DOI: 10.1093/nar/gkt1344

Reiko Mizutani, Takahiro Morimitsu, Katsuyuki Nakashima, and Motoo Tori, Synthesis of a hydrindenone in rings C and D of YW3699, Natural Product Communications 8, 949-953 (2013).

Takahiro Morimitsu, Reiko Mizutani, Katsuyuki Nakashima, Yoshinori Saito, and Motoo Tori, Use of RCM reactions for construction of eight-membered carbocycles and introduction of a hydroxy group at the juncture between five- and eight-membered carbocycles, Natural Product Communications 8, 883-887 (2013).

Katsuyuki Nakashima, Naoki Kikuchi, Tasuku Takehara, Takayuki Shiozawa, Shigeru Takaoka, Motoo Tori, Synthesis of a key intermediate, 10-acetyl-7-(t-butyldiphenylsilyloxymethyl)-4-methylbicyclo[5.3.0]dec-4-en-1-ol, in the synthesis of pseudolaric acid A, Natural Product Communications 8, 877-881 (2013).

Jakub Šebera, Jaroslav Burda, Michal Straka, Akira Ono, Chojiro Kojima, Yoshiyuki Tanaka, and Vladimír Sychrovský, Formation of a Thymine-HgII-Thhymine Metal-Mediated DNA Base Pair; Proposal and Theoretical Calculation of the Reaction Pathway. Chemistry A European Journal 19, 9884-9894 (2013).. DOI: 10.1002/chem.201300460

Kiyofumi Inamoto, Yuta Araki, Shoko Kikkawa, Misato Yonemoto, Yoshiyuki Tanaka, and Yoshinori Kondo, Organocatalytic Functionalization of Heteroaromatic N-Oxides with C-Nucleophiles Using in situ Generated Onium Amide Bases, Organic & Biomolecular Chemistry 11, 4438-4441 (2013). DOI: DOI: 10.1039/c3ob40782a

Misato Yonemoto-Kobayashi, Kiyofumi Inamoto, Yoshiyuki Tanaka, and Yoshinori Kondo, Carboxylation of Alkynylsilanes with Carbon Dioxide Mediated by Cesium Fluoride in DMSO, Organic & Biomolecular Chemistry 11, 3773-3775 (2013). DOI: 10.1039/c3ob40760h

Yoshikazu Hattori, Kyoko Furuita, Izuru Ohki, Takahisa Ikegami, Harumi Fukada, Masahiro Shirakawa, Toshimichi Fujiwara, and Chojiro Kojima, Utilization of lysine 13C-methylation NMR for protein-protein interaction studies, Journal of Biomolecular NMR 55, 19-31 (2013). DOI: 10.1007/s10858-012-9675-9

Jakub Šebera, Lukáš Trantirek, Yoshiyuki Tanaka, and Vladimír Sychrovský, Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N-glycosidic Bond of 8-OxoG with the hOGG1 DNA Repair Protein, Journal of Physical Chemistry B 116, 12535-12544 (2012). DOI: 10.1021/jp309098d

Ladislav Benda, Michal Straka, Vladimír Sychrovský, Petr Bouř, and Yoshiyuki Tanaka, Detection of Mercury-TpT Dinucleotide Binding by the Raman Spectra. A Computational Study, Journal of Physical Chemistry A 116, 8313-8320 (2012).. DOI: DOI: 10.1021/jp3045077

Hidetaka Torigoe, Itaru Okamoto, Takenori Dairaku, Yoshiyuki Tanaka, Akira Ono, and Tstsuo Kozasa, Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C-Ag-C metal-mediated base pair, Biochimie 94, 2431-2440 (2012). DOI: 10.1016/j.biochi.2012.06.024

Hiroshi Abe, Naoko Abe, Aya Shibata, Keiji Ito, Yoshiyuki Tanaka, Mika Ito, Hisao Saneyoshi, Satoshi Shuto, and Yoshihiro Ito, Structure Formation and Catalytic Activity of DNA dissolved in Organic Solvents, Angewandte Chemie International Edition 51, 6475-6479 (2012). DOI: 10.1002/anie.201201111

Tomomi Uchiyama, Takashi Miura, Hideo Takeuchi, Takenori Dairaku, Tomoyuki Komuro, Takuya Kawamura, Yoshinori Kondo, Ladislav Benda, Vladimír Sychrovský, Petr Bouř, Itaru Okamoto, Akira Ono, and Yoshiyuki Tanaka, Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury, Nucleic Acids Research 40, 5766-5774 (2012). DOI: 10.1093/nar/gks208

Ikumi Kawahara, Kaichiro Haruta, Yuta Ashihara, Daichi Yamanaka, Mituhiro Kuriyama, Naoko Toki, Yoshinori Kondo, Kenta Teruya, Junya Ishikawa, Hiroyuki Furuta, Yoshiya Ikawa, Chojiro Kojima, and Yoshiyuki Tanaka, Site-specific isotope labeling of long RNA for structural and mechanistic studies, Nucleic Acids Research 40, e7 (2012). DOI: 10.1093/nar/gkr951)

Akira Ono, Hidetaka Torigoe, Yoshiyuki Tanaka, and Itaru Okamoto, Binding of metal ions by pyrimidine base pairs in DNA duplexes, Chemical Society Reviews 40, 5855-5866 (2011). DOI: 10.1039/c1cs15149e

Ladislav Benda, Michal Straka, Yoshiyuki Tanaka, and Vladimír Sychrovský, On the Role of Mercury in the Non-Covalent Stabilisation of Consecutive U-HgII-U Metal-Mediated Nucleic Acid Base Pairs: Metallophilic Attraction Enters the World of Nucleic Acids, Physical Chemistry Chemical Physics 13, 100-103 (2011). DOI: 10.1039/c0cp01534b

Yuya Egawa, Yoshiyuki Tanaka, Ryota Gotoh, Satoshi Niina, Yu Kojima, Naoki Shimomura, Hiroko Nakagawa, Toshinobu Seki, and Jun-ichi Anzai, Nitrogen-15 NMR Spectroscopy of Sugar Sensor with BN Interaction as a Key Regulator of Colorimetric Signals, Chemistry Letters 39, 1188-1189 (2010)..DOI: 10.1246/cl.2010.1188

Motoo Tori, Kanako Otose, Hiroko Fukuyama, Junko Murata, Yauko Shiotani, Shigeru Takaoka, Katsuyuki Nakashima, Masakazu Sono, Tanaka Sono, and Masami Tanaka, New eremophilanes from Farfugium japonicum Tetrahedron 66(27-28), 5235-5243 (2010). DOI: 10.1016/j.tet.2010.04.079

Junpei Yamamoto, Yoshiyuki Tanaka, and Shigenori Iwai, Spectroscopic analysis of the pyrimidine(6-4)pyrimidone photoproduct: Insights into the (6-4) photolyase reaction, Organic & Biomolecular Chemistry 7, 161-166 (2009). DOI: 10.1039/b815458a9

Reiko Mizutani, Takuo Miki, Katsuyuki; Nakashima, Masakazu Sono, and Motoo Tori, Trisubstituted Double Bond in the Cyclooctene Ring. Preparation Using the RCM Reaction, Heterocycles 78, 2295-2314 (2009). DOI: 10.3987/COM-09-11720

Reiko Mizutani, Katsuyuki Nakashima, Yoshinori Saito, Masakazu Sono, and Motoo Tori, Studies toward the total synthesis of YW3699, a sesterterpenoid GPI biosynthesis inhibitor: preparation of the tri-substituted cyclooctene ring using the RCM reaction, Tetrahedron Letters 50, 2225-2227 (2009). DOI: 10.1016/j.tetlet.2009.02.163

Akira Ono, Shiqi Cao, Humika Togashi, Mitsuru Tashiro, Takashi Fujimoto, Tomoya Machinami, Shuji Oda, Yoko Miyake, Itaru Okamoto, and Yoshiyuki Tanaka, Specific interactions between Silver(I) Ions and Cytosine-Cytosine Pairs in DNA Duplexes, Chemical Communications 39, 4825-4827 (2008). DOI: 10.1039/b808686a

Yoshiyuki Tanaka and Akira Ono, Nitrogen-15 NMR spectroscopy of N-metallated nucleic acids: Insights into 15N NMR parameters and N-metal bonds, Dalton Transactions 37, 4965-4974 (2008). DOI: 10.1039/b803510p

Toshiya Masuda, Kazuki Yamada, Jun Akiyama, Tatsushi Someya,Yuka Odaka, Yoshio Takeda, Motoo Tori, Katsuyuki Nakashima, Tomomi Maekawa, and Yoshiaki Sone, Antioxidation mechanism studies of caffeic acid: identification of antioxidation products of methyl caffeate from lipid oxidation, Agricultural and Food Chemistry 56, 5947-5952 (2008). DOI: 10.1021/jf800781b

Motoo Tori, Norie Morishita, Naoko Hirota, Yoshinori Saito, Katsuyuki Nakashima, Masakazu Sono, Masami Tanaka, Akiko Utagawa, and Hiroshi Hirota, Sesquiterpenoids isolated from Eupatorium glehnii. Isolation of guaiaglehnin A, structure revision of Hiyodorilactone B, and genetic comparison, Chemical & Pharmaceutical Bulletin 56, 677-681 (2008). DOI: 10.1248/cpb.56.677

Motoo Tori, Hiromi Nakamizo, Kanako Mihara, Masahiko Sato, Yasuko Okamoto, Katsuyuki Nakashima, MasamiTanaka, Yoshinori Saito, Masakazu Sono, and Xun Gong, Chemical and genetic diversity of Ligularia vellerea in Yunnan, China, Phytochemistry 69, 1158-1165 (2008). DOI: 10.1016/j.phytochem.2007.12.001

Katsuyuki Nakashima, Naoki Kikuchi, Daisuke Shirayama, Takuo Miki, Kazuhiro Ando, Masakazu Sono, Shinya Suzuki, Masaki Kawase, Masuo Kondoh, Masao Sato, and Motoo Tori, Total Synthesis and Cytotoxicity of (+)- and (–)-Goniodiol and 6-epi-Goniodiol. Construction of α,β-Unsaturated Lactones by Ring-Closing Metathesis, Bulletin of the Chemical Society of Japan 80, 387-394 (2007). DOI: 10.1246/bcsj.80.387

Yoshiyuki Tanaka, Shuji Oda, Hiroshi Yamaguchi, Yoshinori Kondo, Chojiro Kojima, and Akira Ono, 15N-15N J-coupling across HgII: Direct observation of HgII-mediated T-T base pairs in a DNA duplex, Journal of the American Chemical Society 129, 224-225 (2007). DOI: 10.1021/ja065552h

Katsuyuki Nakashima, Norihiro Fujisaki, Kosuke Inoue, Atsushi Minami, Chisako Nagaya, Masakazu Sono, and Motoo Tori, Preparation of Seven-Membered Carbocycles Using Ring-Closing Metathesis Reaction and Application to Syntheses of Tormesol and Cyathane Skeleton, Bulletin of the Chemical Society of Japan 80, 387-394 (2007). DOI: 10.1246/bcsj.79.1955

Yoko Miyake, Humika Togashi, Mitsuru Tashiro, Hiroshi Yamaguchi, Shuji Oda, Megumi Kudo, Yoshiyuki Tanaka, Yoshinori Kondo, Ryuichi Sawa, Takashi Fujimoto, Tomoya Machinami, and Akira Ono, MercuryII-mediated formation of thymine-HgII-thymine base pairs in DNA duplexes, Journal of the American Chemical Society 128, 2172-2173 (2006). DOI: 10.1021/ja056354d

Yoshiyuki Tanaka, Makoto Arakawa, Yohei Yamaguchi, Chieko Hori, Masahiro Ueno, Takeyuki Tanaka, Tatsushi Imahori, and Yoshinori Kondo, NMR spectroscopic observation of a metal-free acetylide anion, Chemistry - An Asian Journal 1, 581-585 (2006). DOI: 10.1002/asia.200600099

Hajime Mita, Takako Ohyama, Yoshiyuki Tanaka, and Yasuhiko Yamamoto, Formation of a Complex of 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin with G-Quadruplex DNA, Biochemistry 45, 6765-6772 (2006). DOI: 10.1021/bi052442z

Yoshiyuki Tanaka, Hiroshi Yamaguchi, Shuji Oda, Makoto Nomura, Chojiro Kojima, Yoshinori Kondo, and Akira Ono, NMR Spectroscopic Study of a DNA Duplex with Mercury-Mediated T-T Base Pairs, Nucleosides, Nucleotides & Nucleic Acids 25, 613-624 (2006). DOI: 10.1080/15257770600686154

Yoshiyuki Tanaka and Kazunari Taira, Detection of RNA nucleobase metalation by NMR spectroscopy, Chemical Communications 16, 2069-2079 (2005). DOI: 10.1039/B415137M

Katsuyuki Nakashima, Sanae Okamoto, Masakazu Sono, and Motoo Tori, Isomerization Reactions of Allylic Alcohols into Ketones with the Grubbs Reagent, Molecules 9, 541-549 (2004). DOI: 10.3390/90700541

Yoshiyuki Tanaka, Yasuhiro Kasai, Shunsuke Mochizuki, Akihiro Wakisaka, Eugene H. Morita, Chojiro Kojima, Atsushi Toyozawa, Yoshinori Kondo, Masumi Taki, Yasuomi Takagi, Atsushi Inoue, Kazuhiko Yamasaki, and Kazunari Taira, Nature of the chemical bond formed with the structural metal ion at the A9/G10.1 motif derived from hammerhead ribozymes, Journal of the American Chemical Society 126, 744-752 (2004). DOI: 10.1021/ja036826t

Yoshiyuki Tanaka, Yasuhiro Kasai, Eugene H. Morita, Chojiro Kojima, Atsushi Toyozawa, Kazuhiko Yamasaki, Kazunari Taira, and Yoshinori Kondo, NMR spectroscopic investigations of the roles of the metal ion at A9/G10.1 site in hammerhead ribozymes, Nucleic Acids Research Supplement 3, 45-46 (2003). DOI: 10.1093/nass/3.1.45

Yoshiyuki Tanaka, Eugene H. Morita, Yasuhiro Kasai, and Kazunari Taira, Divalent cation binding to the well-conserved tandem G-A pairs and flanking C-G pair in hammerhead ribozymes as revealed by heteronuclear NMR spectroscopy, Phosphorus Sulfur and Silicon and the Related elements 177, 2095-2096 (2002). DOI: 10.1080/10426500213301

Yoshiyuki Tanaka, Atsushi Toyozawa, and Yoshinori Kondo, Physicochemical Analysis of Nucleobase-Metal Interactions, Nucleic Acids Research Supplement 2, 187-188 (2002). DOI: 10.1093/nass/2.1.187

Motoo Tori, Yoshiko Takeichi, Hiroe Kuga, Katsuyuki Nakashima, and Masakazu Sono, Seven Germacranolides, Eupaglehnins A, B, C, D, E, and F, and 2α-Acetoxyepitulipinolide from Eupatorium glehni, Chemical and Pharmaceutical Bulletin 50, 1250-1254 (2002). DOI 10.1248/cpb.50.1250

Katsuyuki Nakashima , Kosuke Inoue , Masakazu Sono , and Motoo Tori, Total Synthesis and Absolute Configuration of Liverwort Diterpenes, (−)-13(15)E,16E-3β,4β-Epoxy-18-hydroxysphenoloba-13(15),16-diene and (−)-13(15)Z,16E-3β,4β-Epoxy-18-hydroxysphenoloba-13(15),16-diene, by Use of the Ring Closing Metathesis Reaction Applied to Seven-Membered Carbocycles with a Trisubstituted Double Bond, Journal of Organic Chemistry 67, 6034–6040 (2002). DOI 10.1021/jo020287d

Ken-ichi Suzumura, Koichi Yoshinari, Yoshiyuki Tanaka, Yasuomi Takagi, Yasuhiro Kasai, Masaki Warashina, Tomoko Kuwabara, Masaya Orita, and Kazunari Taira, A Reappraisal, Based on 31P NMR, of the Direct Coordination of a Metal Ion with the Phosphoryl Oxygen at the Cleavage Site of a Hammerhead Ribozyme, Journal of the American Chemical Society 124, 8230-8236 (2002). DOI: 10.1021/ja0202098

Yoshiyuki Tanaka, Chojiro Kojima, Eugene H. Morita, Yasuhiro Kasai, Kazuhiko Yamasaki, Akira Ono, Masatsune Kainosho, and Kazunari Taira, Identification of the Metal Ion Binding Site on an RNA Motif from Hammerhead Ribozyme using 15N-NMR Spectroscopy, Journal of the American Chemical Society 124, 4595-4601 (2002). DOI: 10.1021/ja011520c

Yasuhiro Kasai, Yoshiyuki Tanaka, Eugene H. Morita, Yoshimasa Tanaka, and Kazunari Taira, Physicochemical analysis of the interaction between a metal ion and the metal-ion-binding motif in hammerhead ribozymes, Nucleic Acids Symposium Series 1, 81-82 (2001). DOI: 10.1093/nass/1.1.81

Kazuhiro Yasuno, Toshio Yamazaki, Yoshiyuki Tanaka, Takashi S. Kodama, Akimasa Matsugami, Masato Katahira, Akira Ishihama, and Yoshimasa Kyogoku, Interaction of the C-terminal Domain of the E. coli RNA Polymerase α-Subunit with the UP Element: Recognizing the Backbone Structure in the Minor Groove Surface, Journal of Molecular Biology 306, 213-225 (2001). DOI: 10.1006/jmbi.2000.4369

Yoshiyuki Tanaka, Chojiro Kojima, Toshio Yamazaki, Takashi S. Kodama, Kazuhiro Yasuno, Shin Miyashita, Akira (Mei) Ono, Akira (Sho) Ono, Masatsune Kainosho, and Yoshimasa Kyogoku, Solution Structure of an RNA Duplex Including a C-U Base-Pair, Biochemistry 39, 7074-7080 (2000). DOI: 10.1021/bi000018m

Yoshiyuki Tanaka, Eugene H. Morita, Hidenori Hayashi, Yasuhiro Kasai, Toshiyuki Tanaka, and Kazunari Taira, Well-conserved tandem G-A pairs and the flanking C-G pair in hammerhead ribozymes are sufficient for capture of structurally and catalytically important metal ions, Journal of the American Chemical Society 122, 11303-11310 (2000). DOI: 10.1021/ja001001u

Ken-ichi Suzumura, Masaki Warashina, Koichi Yoshinari, Yoshiyuki Tanaka, Tomoko Kuwabara, Masaya Orita, and Kazunari Taira, Significant change in the structure of a ribozyme upon introduction of a phosphorothioate linkage at P9: NMR reveals a conformational fluctuation in the core region of a hammerhead ribozyme, FEBS Letter 473, 106-112 (2000). DOI: 10.1016/S0014-5793(00)01499-X

Yuka Nakamatsu, Masaki Warashina, Tomoko Kuwabara, Yoshiyuki Tanaka, Koichi Yoshinari, and Kazunari Taira, Significant activity of a modified ribozyme with N7-deazaguanine at G10.1: the double metal ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes, Genes to Cells 5, 603-612 (2000). DOI: 10.1046/j.1365-2443.2000.00352.x

Jing-Min Zhou, Yuka Nakamatsu, Tomoko Kuwabara, Masaki Warashina, Yoshiyuki Tanaka, Koichi Yoshinari, and Kazunari Taira, Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizyme, Journal of Inorganic Biochemistry 78, 261-268 (2000). DOI: 10.1016/S0162-0134(00)00005-2