業績 | 薬品分析学 田中研究室
  • 原著論文・総説


    2017年

    Yoshinori Saito*, Motoki Hidaka, Akané Fukuda, Yasuko Okamoto*, Katsuyuki Nakashima, Motoo Tori, Ryo Hanai*, Xun Gong*, Eiji Watanabe, and Chiaki Kuroda*, Intra-specific diversity of the chemical composition of Ligularia lamarum in the Hengduan Mountains, China: The structures of four new eremophilanes and a new seco-eremophilane, Phytochemistry Letters 20, 139–145 (2017). DOI: 10.1016/j.phytol.2017.04.026

    Yoshikazu Hattori, David Heidenreich, Yuki Ono, Toshihiko Sugiki, Kei‑ichi Yokoyama, Ei‑ichiro Suzuki, Toshimichi Fujiwara, and Chojiro Kojima*, Protein 19F-labeling using transglutaminase for the NMR study of intermolecular interactions, Journal of Biomolecular NMR 68, 271–279 (2017). DOI: 10.1007/s10858-017-0125-6

    Jiro Kondo*, Yoshinari Tada, Takenori Dairaku, Yoshikazu Hattori, Hisao Saneyoshi, Akira Ono, and Yoshiyuki Tanaka, A metallo-DNA nanowire with uninterrupted one-dimensional silver array, Nature Chemistry 9, 956–960 (2017). DOI: 10.1038/nchem.2808
    プレスリリースPDF (上智大) Highlight (ChemBioChem) News and Views (Nature Chemistry)

    Jakub Šebera, Yoshikazu Hattori, Daichi Sato, David Řeha, Radim Nencka, Takashi Kohno, Chojiro Kojima*, Yoshiyuki Tanaka*, and Vladimír Sychrovský*, The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine, Nucleic Acids Research 45, 5231-5242 (2017). DOI: 10.1093/nar/gkx157

  • 2016年

    Kazuki Ishii, Noriko Saito-Tarashima, Masashi Ota, Seigi Yamamoto, Yasuko Okamoto, Yoshiyuki Tanaka, and Noriaki Minakawa*, Practical synthesis of 4'-selenopurine nucleosides by combining chlorinated purines and 'armed' 4-selenosugar, Tetrahedron 72, 6589-6594 (2016). DOI: 10.1016/j.tet.2016.08.071

    Katsuyuki Nakashima, Hatsuna Matsunaga, Masako Ito, Hiroshi Minami, Akihito Aiba, Norihiro Fujisaki, and Motoo Tori, Macrocyclization Using RCM Reactions. Synthesis of Simple Metacyclophanes and Synthetic Efforts Toward Platycarynol, a 15-Membered Aromatic Ether, Natural Product Communications 11, 1135-1142 (2016).

    Takenori Dairaku*, Kyoko Furuita, Hajime Sato, Jakub Šebera, Katsuyuki Nakashima, Jiro Kondo, Daichi Yamanaka, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Vladimír Sychrovský*, Chojiro Kojima*, and Yoshiyuki Tanaka*, Structure Determination of an AgI-Mediated Cytosine–Cytosine Base Pair within DNA Duplex in Solution with 1H/15N/109Ag NMR Spectroscopy, Chemistry A Europian Journal 22, 13028–13031 (2016). DOI: 10.1002/chem.201603048

    Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Šebera, Katsuyuki Nakashima, Akira Ono, Vladimír Sychrovský, Chojiro Kojima, and Yoshiyuki Tanaka*, Hg II /Ag I-mediated base pairs and their NMR spectroscopic studies, Inorganica Chimica Acta 452, 34-42 (2016). DOI: 10.1016/j.ica.2016.03.018

    Jakub Šebera, Yoshiyuki Tanaka, Akira Ono, and Vladimír Sychrovský*, The effect of chemical modification of DNA base on binding of Hg II and Ag I in metal-mediated base pairs, Inorganica Chimica Acta 452, 199-204 (2016). DOI: 10.1016/j.ica.2016.03.007

    Yasuko Okamoto, Mizuho Taniguchi, Katsuyuki Nakashima, Xun Gong, Ryo Hanai, Chiaki Kuroda, and Motoo Tori, Chemical Constituents of Ligularia wilsoniana Collected in Chongqing, China, Natural Product Communications 11, 149-152 (2016).

    Yasuko Okamoto, Mizuho Taniguchi, Kaori Terada, Katsuyuki Nakashima, Xun Gong, Ryo Hanai, Motoo Tori, and Chiaki Kuroda, Diversity in Chemical Constituents of Ligularia longihastata Collected in China, Natural Product Communications 11, 145-148 (2016).

    Martin Dracinsky, Michal Sala, Blanka Klepetarova, Jakub Šebera, Jiri Fukal, Veronika Holeckova, Yoshiyuki Tanaka, Radim Nencka, and Vladimír Sychrovský*, Benchmark Theoretical and Experimental Study on 15N NMR Shifts of Oxidatively Damaged Guanine, The Journal of Physical Chemistry B 120, 915-925 (2016). DOI: 10.1021/acs.jpcb.5b11428

  • 2015年

    Yoshinori Saito, Saori Iga, Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong*, Chiaki Kuroda*, and Motoo Tori*, Terpenoids from Ligularia virgaurea collected in China: the first example of two bakkane derivatives with an anhydride-type ring C and nineteen new chemical constituents, Tetrahedron 44, 8428-8435 (2015). DOI: 10.1016/j.tet.2015.09.011

    Yoshiyuki Tanaka*, Jiro Kondo, Vladimír Sychrovský, Jakub Šebera, Takenori Dairaku, Hisao Saneyoshi, Hidehito Urata, Hidetaka Torigoe, and Akira Ono*, Structures, physicochemical properties, and applications of T-Hg II-T, C-Ag I-C, and other metallo-base-pairs, Chemical Communications 51, 17343-17360 (2015). DOI: 10.1039/C5CC02693H

    Jiro Kondo*, Yoshinari Tada, Takenori Dairaku, Hisao Saneyoshi, Itaru Okamoto, Yoshiyuki Tanaka, and Akira Ono, High-resolution Crystal Structure of Silver(I)-RNA Hybrid Duplex Containing Watson-Crick-like C-Silver(I)-C Metallo-Base Pairs, Angewandte Chemie International Edition 54, 13323-13326 (2015).. DOI: 10.1002/anie.201507894

    Takenori Dairaku, Kyoko Furuita, Hajime Sato, Yoshinori Kondo, Chojiro Kojima, Akira Ono, and Yoshiyuki Tanaka*, Exploring a DNA Sequence for the Three-Dimensional Structure Determination of a Silver(I)-Mediated C-C Base Pair in a DNA Duplex by 1H NMR Spectroscopy, Nucleosides, Nucleotides & Nucleic Acids 34, 877-900 (2015). DOI: 10.1080/15257770.2015.1088160

    Katsuyuki Nakashima, Hiroyuki Kawano, Minako Kumano, Hikari Kodama, Masayo Kameoka, Akiyo Yamamoto, Reiko Mizutani, Masakazu Sono, and Motoo Tori*, What is the absolute configuration of (+)-crispatanolide isolated from Makinoa crispata (liverwort)? Tetrahedron Letters 56, 49112-4915 (2015). DOI: 10.1016/j.tetlet.2015.06.083

    Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Šebera, Daichi Yamanaka, Hiroyuki Otaki, Shoko Kikkawa, Yoshinori Kondo, Ritsuko Katahira, F. Matthias Bickelhaupt, Celia Fonseca Guerra, Akira Ono, Vladimír Sychrovský*, Chojiro Kojima*, and Yoshiyuki Tanaka*, Direct detection of the mercury-nitrogen bond in the thymine-Hg II-thymine base-pair with 199Hg NMR spectroscopy, Chemical Communications 51, 8488-8491 (2015). DOI: 10.1039/c5cc02423d

    Yoshinori Saito, Takanori Otsubo, Yuko Iwamoto,Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong, Chiaki Kuroda, and Motoo Tori, Four New Sesquiterpenoids from Ligularia subspicata Collected in China; Isolation of a Bakkane-type Lactone, an Eremophilane-type Lactone, and Two Ortho Esters, Natural Product Communications 10, 831-833 (2015).

    Mizuho Taniguchi, Katsuyuki Nakashima, Yasuko Okamoto, Xun Gong, Chiaki Kuroda, and Motoo Tori, Constituents of Ligularia brassicoides Collected in China: A New Diels-Alder Adduct of Eremophilan-10β-ol and Methacrylic Acid, Natural Product Communications 10, 827-830 (2015).,

    Katsuyuki Nakashima, Yuzuru Kondo, Kosei Yoshimasu, Masakazu Sono, and Motoo Tori, Synthesis of chiral hexasubstituted cyclohexanediol, a key intermediate for the synthesis of verticillol, from (+)-dihydrocarvone; attempted cyclization to 12-membered carbocycle in verticillol using RCM reaction, Natural Product Communications 10, 551-555 (2015).


  • 所属教員の以前の業績

    2014年

    Saori Kataoka, Kyoko Furuita, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, and Chojiro Kojima, 1H, 15N and 13C resonance assignments of the conserved region in the middle domain of S. pombe Sin1 protein, Biomolecular NMR Assignment 9, 89-92 (2015). DOI: 10.1007/s12104-014-9550-6

    Kyoko Furuita, Saori Kataoka, Toshihiko Sugiki, Yoshikazu Hattori, Naohiro Kobayashi, Takahisa Ikegami, Kazuhiro Shiozaki, Toshimichi Fujiwara, and Chojiro Kojima, Utilization of paramagnetic relaxation enhancements for high-resolution NMR structure determination of a soluble loop-rich protein with sparse NOE distance restraints, Journal of Biomolecular NMR 61, 55-64 (2015). DOI: 10.1007/s10858-014-9882-7

    Jakub Šebera, Lukáš Trantírek, Yoshiyuki Tanaka, Radim Nencka, Jiří Fukal, and Vladimír Sychrovský, The activation of N-glycosidic bond cleavage operated by base-excision repair enzyme hOGG1; theoretical study of the role of Lys 249 residue in activation of G, OxoG and FapyG, RSC Advances 4, 44043-44051 (2014). DOI: 10.1039/C4RA08278H

    Mituhiro Kuriyama, Yoshinori Kondo, and Yoshiyuki Tanaka, Pseudoknot interaction-mediated activation of type I hammerhead ribozyme: A new class of gene-therapeutic agents, Nucleosides, Nucleotides & Nucleic Acids 33, 466-480 (2014). DOI: 10.1080/15257770.2014.887098

    Mituhiro Kuriyama, Kaichiro Haruta, Takenori Dairaku, Takuya Kawamura, Shoko Kikkawa, Kiyofumi Inamoto, Hirokazu Tsukamoto, Yoshinori Kondo, Hidetaka Torigoe, Itaru Okamoto, Akira Ono, Eugene H. Morita, and Yoshiyuki Tanaka, Hg2+ -trapping Beads: Hg2+ -specific Recognition through Thymine-Hg(II)-Thymine Base Pairing, Chemical Pharmaceutical Bulletin 62, 709-712 (2014). DOI: 10.1248/cpb.c13-00918

    Jakub Šebera, Lukáš Trantirek, Jiří Fukal, Yoshiyuki Tanaka, and Vladimír Sychrovský, Mechanism of base excision with the hOGG1 DNA repair enzyme Chemicke Listy 108, 364-367 (2014).

    Irena Kratochvílová, Martin Golan, Martin Vala, Miroslava Špérová, Martin Weiter, Ondrej Páv, Jakub Šebera, Ivan Rosenberg, Vladimír Sychrovský, Yoshiyuki Tanaka, and F. Matthias Bickelhaupt, Theoretical and Experimental Study of Charge Transfer through DNA: Impact of Mercury Mediated T-Hg-T Base Pair, The Journal of Physical Chemistry B 118, 5374-5381 (2014).. DOI: 10.1021/jp501986a

    Jiro Kondo, Tom Yamada, Chika Hirose, Itaru Okamoto, Yoshiyuki Tanaka, and Akira Ono, Crystal Structure of Metallo-DNA Duplex Containing Consecutive Watson-Crick-like T-Hg(II)-T Base Pairs, Angewandte Chemie International Edition 53, 2385-2388 (2014). DOI: 10.1002/anie.201309066

    Hiroshi Yamaguchi, Jakub Šebera, Jiro Kondo, Shuji Oda, Tomoyuki Komuro, Takuya Kawamura, Takenori Daraku, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Jaroslav V. Burda, Chojiro Kojima, Vladimír Sychrovský, and Yoshiyuki Tanaka, The structure of metallo-DNA with consecutive T-HgII-T base-pairs explains positive entropy for the metallo-base-pair formation, Nucleic Acids Research 42, 4094-4099 (2014). DOI: 10.1093/nar/gkt1344

  • 2013年

    Reiko Mizutani, Takahiro Morimitsu, Katsuyuki Nakashima, and Motoo Tori, Synthesis of a hydrindenone in rings C and D of YW3699, Natural Product Communications 8, 949-953 (2013).

    Takahiro Morimitsu, Reiko Mizutani, Katsuyuki Nakashima, Yoshinori Saito, and Motoo Tori, Use of RCM reactions for construction of eight-membered carbocycles and introduction of a hydroxy group at the juncture between five- and eight-membered carbocycles, Natural Product Communications 8, 883-887 (2013).

    Katsuyuki Nakashima, Naoki Kikuchi, Tasuku Takehara, Takayuki Shiozawa, Shigeru Takaoka, Motoo Tori, Synthesis of a key intermediate, 10-acetyl-7-(t-butyldiphenylsilyloxymethyl)-4-methylbicyclo[5.3.0]dec-4-en-1-ol, in the synthesis of pseudolaric acid A, Natural Product Communications 8, 877-881 (2013).

    Jakub Šebera, Jaroslav Burda, Michal Straka, Akira Ono, Chojiro Kojima, Yoshiyuki Tanaka, and Vladimír Sychrovský, Formation of a Thymine-HgII-Thhymine Metal-Mediated DNA Base Pair; Proposal and Theoretical Calculation of the Reaction Pathway. Chemistry A European Journal 19, 9884-9894 (2013).. DOI: 10.1002/chem.201300460

    Kiyofumi Inamoto, Yuta Araki, Shoko Kikkawa, Misato Yonemoto, Yoshiyuki Tanaka, and Yoshinori Kondo, Organocatalytic Functionalization of Heteroaromatic N-Oxides with C-Nucleophiles Using in situ Generated Onium Amide Bases, Organic & Biomolecular Chemistry 11, 4438-4441 (2013). DOI: DOI: 10.1039/c3ob40782a

    Misato Yonemoto-Kobayashi, Kiyofumi Inamoto, Yoshiyuki Tanaka, and Yoshinori Kondo, Carboxylation of Alkynylsilanes with Carbon Dioxide Mediated by Cesium Fluoride in DMSO, Organic & Biomolecular Chemistry 11, 3773-3775 (2013). DOI: 10.1039/c3ob40760h

    Yoshikazu Hattori, Kyoko Furuita, Izuru Ohki, Takahisa Ikegami, Harumi Fukada, Masahiro Shirakawa, Toshimichi Fujiwara, and Chojiro Kojima, Utilization of lysine 13C-methylation NMR for protein-protein interaction studies, Journal of Biomolecular NMR 55, 19-31 (2013). DOI: 10.1007/s10858-012-9675-9

  • 2012年

    Jakub Šebera, Lukáš Trantirek, Yoshiyuki Tanaka, and Vladimír Sychrovský, Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N-glycosidic Bond of 8-OxoG with the hOGG1 DNA Repair Protein, Journal of Physical Chemistry B 116, 12535-12544 (2012). DOI: 10.1021/jp309098d

    Ladislav Benda, Michal Straka, Vladimír Sychrovský, Petr Bouř, and Yoshiyuki Tanaka, Detection of Mercury-TpT Dinucleotide Binding by the Raman Spectra. A Computational Study, Journal of Physical Chemistry A 116, 8313-8320 (2012).. DOI: DOI: 10.1021/jp3045077

    Hidetaka Torigoe, Itaru Okamoto, Takenori Dairaku, Yoshiyuki Tanaka, Akira Ono, and Tstsuo Kozasa, Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C-Ag-C metal-mediated base pair, Biochimie 94, 2431-2440 (2012). DOI: 10.1016/j.biochi.2012.06.024

    Hiroshi Abe, Naoko Abe, Aya Shibata, Keiji Ito, Yoshiyuki Tanaka, Mika Ito, Hisao Saneyoshi, Satoshi Shuto, and Yoshihiro Ito, Structure Formation and Catalytic Activity of DNA dissolved in Organic Solvents, Angewandte Chemie International Edition 51, 6475-6479 (2012). DOI: 10.1002/anie.201201111

    Tomomi Uchiyama, Takashi Miura, Hideo Takeuchi, Takenori Dairaku, Tomoyuki Komuro, Takuya Kawamura, Yoshinori Kondo, Ladislav Benda, Vladimír Sychrovský, Petr Bouř, Itaru Okamoto, Akira Ono, and Yoshiyuki Tanaka, Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury, Nucleic Acids Research 40, 5766-5774 (2012). DOI: 10.1093/nar/gks208

    Ikumi Kawahara, Kaichiro Haruta, Yuta Ashihara, Daichi Yamanaka, Mituhiro Kuriyama, Naoko Toki, Yoshinori Kondo, Kenta Teruya, Junya Ishikawa, Hiroyuki Furuta, Yoshiya Ikawa, Chojiro Kojima, and Yoshiyuki Tanaka, Site-specific isotope labeling of long RNA for structural and mechanistic studies, Nucleic Acids Research 40, e7 (2012). DOI: 10.1093/nar/gkr951)

  • 2011年

    Akira Ono, Hidetaka Torigoe, Yoshiyuki Tanaka, and Itaru Okamoto, Binding of metal ions by pyrimidine base pairs in DNA duplexes, Chemical Society Reviews 40, 5855-5866 (2011). DOI: 10.1039/c1cs15149e

    Ladislav Benda, Michal Straka, Yoshiyuki Tanaka, and Vladimír Sychrovský, On the Role of Mercury in the Non-Covalent Stabilisation of Consecutive U-HgII-U Metal-Mediated Nucleic Acid Base Pairs: Metallophilic Attraction Enters the World of Nucleic Acids, Physical Chemistry Chemical Physics 13, 100-103 (2011). DOI: 10.1039/c0cp01534b

  • 2010年

    Yuya Egawa, Yoshiyuki Tanaka, Ryota Gotoh, Satoshi Niina, Yu Kojima, Naoki Shimomura, Hiroko Nakagawa, Toshinobu Seki, and Jun-ichi Anzai, Nitrogen-15 NMR Spectroscopy of Sugar Sensor with BN Interaction as a Key Regulator of Colorimetric Signals, Chemistry Letters 39, 1188-1189 (2010)..DOI: 10.1246/cl.2010.1188

    Motoo Tori, Kanako Otose, Hiroko Fukuyama, Junko Murata, Yauko Shiotani, Shigeru Takaoka, Katsuyuki Nakashima, Masakazu Sono, Tanaka Sono, and Masami Tanaka, New eremophilanes from Farfugium japonicum Tetrahedron 66(27-28), 5235-5243 (2010). DOI: 10.1016/j.tet.2010.04.079

  • 2009年

    Junpei Yamamoto, Yoshiyuki Tanaka, and Shigenori Iwai, Spectroscopic analysis of the pyrimidine(6-4)pyrimidone photoproduct: Insights into the (6-4) photolyase reaction, Organic & Biomolecular Chemistry 7, 161-166 (2009). DOI: 10.1039/b815458a9

    Reiko Mizutani, Takuo Miki, Katsuyuki; Nakashima, Masakazu Sono, and Motoo Tori, Trisubstituted Double Bond in the Cyclooctene Ring. Preparation Using the RCM Reaction, Heterocycles 78, 2295-2314 (2009). DOI: 10.3987/COM-09-11720

    Reiko Mizutani, Katsuyuki Nakashima, Yoshinori Saito, Masakazu Sono, and Motoo Tori, Studies toward the total synthesis of YW3699, a sesterterpenoid GPI biosynthesis inhibitor: preparation of the tri-substituted cyclooctene ring using the RCM reaction, Tetrahedron Letters 50, 2225-2227 (2009). DOI: 10.1016/j.tetlet.2009.02.163

  • 2008年

    Akira Ono, Shiqi Cao, Humika Togashi, Mitsuru Tashiro, Takashi Fujimoto, Tomoya Machinami, Shuji Oda, Yoko Miyake, Itaru Okamoto, and Yoshiyuki Tanaka, Specific interactions between Silver(I) Ions and Cytosine-Cytosine Pairs in DNA Duplexes, Chemical Communications 39, 4825-4827 (2008). DOI: 10.1039/b808686a

    Yoshiyuki Tanaka and Akira Ono, Nitrogen-15 NMR spectroscopy of N-metallated nucleic acids: Insights into 15N NMR parameters and N-metal bonds, Dalton Transactions 37, 4965-4974 (2008). DOI: 10.1039/b803510p

    Toshiya Masuda, Kazuki Yamada, Jun Akiyama, Tatsushi Someya,Yuka Odaka, Yoshio Takeda, Motoo Tori, Katsuyuki Nakashima, Tomomi Maekawa, and Yoshiaki Sone, Antioxidation mechanism studies of caffeic acid: identification of antioxidation products of methyl caffeate from lipid oxidation, Agricultural and Food Chemistry 56, 5947-5952 (2008). DOI: 10.1021/jf800781b

    Motoo Tori, Norie Morishita, Naoko Hirota, Yoshinori Saito, Katsuyuki Nakashima, Masakazu Sono, Masami Tanaka, Akiko Utagawa, and Hiroshi Hirota, Sesquiterpenoids isolated from Eupatorium glehnii. Isolation of guaiaglehnin A, structure revision of Hiyodorilactone B, and genetic comparison, Chemical & Pharmaceutical Bulletin 56, 677-681 (2008). DOI: 10.1248/cpb.56.677

    Motoo Tori, Hiromi Nakamizo, Kanako Mihara, Masahiko Sato, Yasuko Okamoto, Katsuyuki Nakashima, MasamiTanaka, Yoshinori Saito, Masakazu Sono, and Xun Gong, Chemical and genetic diversity of Ligularia vellerea in Yunnan, China, Phytochemistry 69, 1158-1165 (2008). DOI: 10.1016/j.phytochem.2007.12.001

  • 2007年

    Katsuyuki Nakashima, Naoki Kikuchi, Daisuke Shirayama, Takuo Miki, Kazuhiro Ando, Masakazu Sono, Shinya Suzuki, Masaki Kawase, Masuo Kondoh, Masao Sato, and Motoo Tori, Total Synthesis and Cytotoxicity of (+)- and (–)-Goniodiol and 6-epi-Goniodiol. Construction of α,β-Unsaturated Lactones by Ring-Closing Metathesis, Bulletin of the Chemical Society of Japan 80, 387-394 (2007). DOI: 10.1246/bcsj.80.387

    Yoshiyuki Tanaka, Shuji Oda, Hiroshi Yamaguchi, Yoshinori Kondo, Chojiro Kojima, and Akira Ono, 15N-15N J-coupling across HgII: Direct observation of HgII-mediated T-T base pairs in a DNA duplex, Journal of the American Chemical Society 129, 224-225 (2007). DOI: 10.1021/ja065552h

  • 2006年

    Katsuyuki Nakashima, Norihiro Fujisaki, Kosuke Inoue, Atsushi Minami, Chisako Nagaya, Masakazu Sono, and Motoo Tori, Preparation of Seven-Membered Carbocycles Using Ring-Closing Metathesis Reaction and Application to Syntheses of Tormesol and Cyathane Skeleton, Bulletin of the Chemical Society of Japan 80, 387-394 (2007). DOI: 10.1246/bcsj.79.1955

    Yoko Miyake, Humika Togashi, Mitsuru Tashiro, Hiroshi Yamaguchi, Shuji Oda, Megumi Kudo, Yoshiyuki Tanaka, Yoshinori Kondo, Ryuichi Sawa, Takashi Fujimoto, Tomoya Machinami, and Akira Ono, MercuryII-mediated formation of thymine-HgII-thymine base pairs in DNA duplexes, Journal of the American Chemical Society 128, 2172-2173 (2006). DOI: 10.1021/ja056354d

    Yoshiyuki Tanaka, Makoto Arakawa, Yohei Yamaguchi, Chieko Hori, Masahiro Ueno, Takeyuki Tanaka, Tatsushi Imahori, and Yoshinori Kondo, NMR spectroscopic observation of a metal-free acetylide anion, Chemistry - An Asian Journal 1, 581-585 (2006). DOI: 10.1002/asia.200600099

    Hajime Mita, Takako Ohyama, Yoshiyuki Tanaka, and Yasuhiko Yamamoto, Formation of a Complex of 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin with G-Quadruplex DNA, Biochemistry 45, 6765-6772 (2006). DOI: 10.1021/bi052442z

    Yoshiyuki Tanaka, Hiroshi Yamaguchi, Shuji Oda, Makoto Nomura, Chojiro Kojima, Yoshinori Kondo, and Akira Ono, NMR Spectroscopic Study of a DNA Duplex with Mercury-Mediated T-T Base Pairs, Nucleosides, Nucleotides & Nucleic Acids 25, 613-624 (2006). DOI: 10.1080/15257770600686154

  • 2005年

    Yoshiyuki Tanaka and Kazunari Taira, Detection of RNA nucleobase metalation by NMR spectroscopy, Chemical Communications 16, 2069-2079 (2005). DOI: 10.1039/B415137M

  • 2004年

    Katsuyuki Nakashima, Sanae Okamoto, Masakazu Sono, and Motoo Tori, Isomerization Reactions of Allylic Alcohols into Ketones with the Grubbs Reagent, Molecules 9, 541-549 (2004). DOI: 10.3390/90700541

    Yoshiyuki Tanaka, Yasuhiro Kasai, Shunsuke Mochizuki, Akihiro Wakisaka, Eugene H. Morita, Chojiro Kojima, Atsushi Toyozawa, Yoshinori Kondo, Masumi Taki, Yasuomi Takagi, Atsushi Inoue, Kazuhiko Yamasaki, and Kazunari Taira, Nature of the chemical bond formed with the structural metal ion at the A9/G10.1 motif derived from hammerhead ribozymes, Journal of the American Chemical Society 126, 744-752 (2004). DOI: 10.1021/ja036826t

  • 2003年

    Yoshiyuki Tanaka, Yasuhiro Kasai, Eugene H. Morita, Chojiro Kojima, Atsushi Toyozawa, Kazuhiko Yamasaki, Kazunari Taira, and Yoshinori Kondo, NMR spectroscopic investigations of the roles of the metal ion at A9/G10.1 site in hammerhead ribozymes, Nucleic Acids Research Supplement 3, 45-46 (2003). DOI: 10.1093/nass/3.1.45

  • 2002年

    Yoshiyuki Tanaka, Eugene H. Morita, Yasuhiro Kasai, and Kazunari Taira, Divalent cation binding to the well-conserved tandem G-A pairs and flanking C-G pair in hammerhead ribozymes as revealed by heteronuclear NMR spectroscopy, Phosphorus Sulfur and Silicon and the Related elements 177, 2095-2096 (2002). DOI: 10.1080/10426500213301

    Yoshiyuki Tanaka, Atsushi Toyozawa, and Yoshinori Kondo, Physicochemical Analysis of Nucleobase-Metal Interactions, Nucleic Acids Research Supplement 2, 187-188 (2002). DOI: 10.1093/nass/2.1.187

    Motoo Tori, Yoshiko Takeichi, Hiroe Kuga, Katsuyuki Nakashima, and Masakazu Sono, Seven Germacranolides, Eupaglehnins A, B, C, D, E, and F, and 2α-Acetoxyepitulipinolide from Eupatorium glehni, Chemical and Pharmaceutical Bulletin 50, 1250-1254 (2002). DOI 10.1248/cpb.50.1250

    Katsuyuki Nakashima , Kosuke Inoue , Masakazu Sono , and Motoo Tori, Total Synthesis and Absolute Configuration of Liverwort Diterpenes, (−)-13(15)E,16E-3β,4β-Epoxy-18-hydroxysphenoloba-13(15),16-diene and (−)-13(15)Z,16E-3β,4β-Epoxy-18-hydroxysphenoloba-13(15),16-diene, by Use of the Ring Closing Metathesis Reaction Applied to Seven-Membered Carbocycles with a Trisubstituted Double Bond, Journal of Organic Chemistry 67, 6034–6040 (2002). DOI 10.1021/jo020287d

    Ken-ichi Suzumura, Koichi Yoshinari, Yoshiyuki Tanaka, Yasuomi Takagi, Yasuhiro Kasai, Masaki Warashina, Tomoko Kuwabara, Masaya Orita, and Kazunari Taira, A Reappraisal, Based on 31P NMR, of the Direct Coordination of a Metal Ion with the Phosphoryl Oxygen at the Cleavage Site of a Hammerhead Ribozyme, Journal of the American Chemical Society 124, 8230-8236 (2002). DOI: 10.1021/ja0202098

    Yoshiyuki Tanaka, Chojiro Kojima, Eugene H. Morita, Yasuhiro Kasai, Kazuhiko Yamasaki, Akira Ono, Masatsune Kainosho, and Kazunari Taira, Identification of the Metal Ion Binding Site on an RNA Motif from Hammerhead Ribozyme using 15N-NMR Spectroscopy, Journal of the American Chemical Society 124, 4595-4601 (2002). DOI: 10.1021/ja011520c

  • 2001年

    Yasuhiro Kasai, Yoshiyuki Tanaka, Eugene H. Morita, Yoshimasa Tanaka, and Kazunari Taira, Physicochemical analysis of the interaction between a metal ion and the metal-ion-binding motif in hammerhead ribozymes, Nucleic Acids Research Supplement 1, 81-82 (2001). DOI: 10.1093/nass/1.1.81

    Kazuhiro Yasuno, Toshio Yamazaki, Yoshiyuki Tanaka, Takashi S. Kodama, Akimasa Matsugami, Masato Katahira, Akira Ishihama, and Yoshimasa Kyogoku, Interaction of the C-terminal Domain of the E. coli RNA Polymerase α-Subunit with the UP Element: Recognizing the Backbone Structure in the Minor Groove Surface, Journal of Molecular Biology 306, 213-225 (2001). DOI: 10.1006/jmbi.2000.4369

  • 2000年

    Yoshiyuki Tanaka, Chojiro Kojima, Toshio Yamazaki, Takashi S. Kodama, Kazuhiro Yasuno, Shin Miyashita, Akira (Mei) Ono, Akira (Sho) Ono, Masatsune Kainosho, and Yoshimasa Kyogoku, Solution Structure of an RNA Duplex Including a C-U Base-Pair, Biochemistry 39, 7074-7080 (2000). DOI: 10.1021/bi000018m

    Yoshiyuki Tanaka, Eugene H. Morita, Hidenori Hayashi, Yasuhiro Kasai, Toshiyuki Tanaka, and Kazunari Taira, Well-conserved tandem G-A pairs and the flanking C-G pair in hammerhead ribozymes are sufficient for capture of structurally and catalytically important metal ions, Journal of the American Chemical Society 122, 11303-11310 (2000). DOI: 10.1021/ja001001u

    Ken-ichi Suzumura, Masaki Warashina, Koichi Yoshinari, Yoshiyuki Tanaka, Tomoko Kuwabara, Masaya Orita, and Kazunari Taira, Significant change in the structure of a ribozyme upon introduction of a phosphorothioate linkage at P9: NMR reveals a conformational fluctuation in the core region of a hammerhead ribozyme, FEBS Letter 473, 106-112 (2000). DOI: 10.1016/S0014-5793(00)01499-X

    Yuka Nakamatsu, Masaki Warashina, Tomoko Kuwabara, Yoshiyuki Tanaka, Koichi Yoshinari, and Kazunari Taira, Significant activity of a modified ribozyme with N7-deazaguanine at G10.1: the double metal ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes, Genes to Cells 5, 603-612 (2000). DOI: 10.1046/j.1365-2443.2000.00352.x

    Jing-Min Zhou, Yuka Nakamatsu, Tomoko Kuwabara, Masaki Warashina, Yoshiyuki Tanaka, Koichi Yoshinari, and Kazunari Taira, Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizyme, Journal of Inorganic Biochemistry 78, 261-268 (2000). DOI: 10.1016/S0162-0134(00)00005-2


  • 著書・紀要・邦文総説

    服部良一,児嶋長次郎,リジン残基13Cメチル化NMR法による相互作用解析と構造変化の検出,生物物理 56, 288-289 (2016). DOI: 10.2142/biophys.56.288

    田中好幸,DNA分子を利用した水銀除染法及び機能性核酸構造解析法の開発研究,The ANNALS of Intelligent Cosmos Academic Foundation 14, 9-12 (2010).

    Yoshiyuki Tanaka and Akira Ono, Structural Studies on MercuryII-mediated T-T Base-pair with NMR Spectroscopy (Chapter 16), In Nick Hadjiliadis and Einar Sletten Eds., "Metal Complexes - DNA Interactions", John Wiley & Sons, West Sussex, UK (2009). DOI: 10.1002/9781444312089

    Ikumi kawahara, Kaichiro Haruta, Chojiro Kojima, and Yoshiyuki Tanaka, NMR studies of HAC1 mRNA, Nucleic Acids Symposium Series 53, 269-270 (2009).

    Hisaaki Tateoka, Ikumi Kawahara, Satomi Hasegawa, Kaichiro Haruta, Yoshinori Kondo, Chojiro Kojima, and Yoshiyuki Tanaka, Preparations of hammerhead ribozymes for investigations of their cleavable sequences, Nucleic Acids Symposium Series 53, 277-278 (2009).

    田中好幸,核酸分子の生理活性の化学的解剖-金属イオンとの相互作用研究から見えてきたもの-,生命化学研究レター 26, 16-23, (2008).

    田中好幸,鳥越秀峰,小野晶,新規ナノデバイス材料としてのメタロDNA分子の構造,生物物理 48, 119-124 (2008). DOI: 10.2142/biophys.48.119

    Yoshiyuki Tanaka, Eugene H. Morita, Kenta Teruya, Takashi S. Kodama, and Takeyuki Tanaka, Spectroscopic and theoretical studies of biological macromolecules: Toward understanding molecular machinery in life, Recent Research Developments in Physical Chemistry, Vol. 9, 1-59 Transworld Research Network, India (2007).

    田中好幸,春田佳一郎,遺伝子治療薬としての酵素RNA分子(リボザイム)の構造,医薬ジャーナル 43, 5-14, 医薬ジャーナル社,大阪 (2007).

    田中好幸,RNAによるRNAの連結反応:リガーゼ活性を有する酵素RNA分子の三次元構造,化学 62, 62-63, 化学同人,京都 (2007).

    Kaichiro Haruta, Yoshiyuki Tanaka, Takuya Kawamura, Yoshinori Kondo, Akira Ono, Hiroyuki Yamakoshi, Naoki Kanoh, amd Yoshiharu Iwabuchi, Synthesis of an enantiomeric DNA oligomer and its T-HgII-T base-pair formation, Nucleic Acids Symposium Series 51, 187-188 (2007).

    Yoshiyuki Tanaka, Shuji Oda, Hiroshi Yamaguchi, Kaichiro Haruta, Takuya Kawamura, Yoshinori Kondo, Tomomi Uchiyama, Takashi Miura, Hideo Takeuchi, Hidetaka Torigoe, Chojiro Kojima, and Akira Ono, Structural and physicochemical features on the metal-mediated base pairs, Nucleic Acids Symposium Series 51, 75-76 (2007).

    Junpei Yamamoto, Yoshiyuki Tanaka, Kenichi Hitomi, Elizabeth D. Getzoff, and Shigenori Iwai, Spectroscopic studies on a novel intramolecular hydrogen bond within the (6-4) photoproduct, Nucleic Acids Symposium Series 51, 79-80 (2007)..

    根東義則,田中好幸,有機塩基のチャンピオン-最も強いブレンステッド塩基性を示す有機化合物-,化学 61, 66-67 化学同人,京都 (2006).

    Yoshiyuki Tanaka, Shuji Oda, Hiroshi Yamaguchi, Megumi Kudo, Yoshinori Kondo, Chojiro Kojima, and Akira Ono, Structural analyses on th mercuryII-mediated T-T base pair, Nucleic Acids Symposium Series, Nucleic Acids Symposium Series 50, 47-48 (2006).

    Shuji Oda, Tomoyuki Komuro, Yoshinori Kondo, Akira Ono, and Yoshiyuki Tanaka, Spectroscopic analysis of AgI-DNA complex, Nucleic Acids Symposium Series 50, 199-200 (2006).

    田中好幸,核酸合成法とその応用 (4章3節1項),生物工学ハンドブック,(塩谷捨明 編) コロナ社,東京 (2005).

    Yoshiyuki Tanaka and Kazunari Taira, Detection of RNA metallation by heteronuclear multidimensional NMR spectroscopy, Recent Research Developments in Organic Chemistry, Vol. 9, 93-118, Transworld Research Network, India (2005).

    根東義則,上野正弘,田中好幸,有機超強塩基を用いる有機合成反応,有機合成化学協会誌 63, 453-463 (2005). DOI: 10.5059/yukigoseikyokaishi.63.453

    Yoshiyuki Tanaka, Hiroshi Yamaguchi, Shuji Oda, Chojiro Kojima, Akira Ono, Kazunari Taira, and Yoshinori Kondo, NMR spectroscopic analyses of functional nucleic acids-metal interaction and their solution structure analyses, Nucleic Acids Symposium Series 49, 51-52 (2005).

    Hiroshi Yamaguchi, Shuji Oda, Chojiro Kojima, Akira Ono, Yoshinori Kondo and Yoshiyuki Tanaka, Spectroscopic analyses of DNA duplexes in the presence of mercury ions, Nucleic Acids Symposium Series 49, 199-200 (2005).

    Makoto Miyagishi, Sahohime Matsumoto, Hideo Akashi, Hiroaki Kawasaki, Taro Fukao, Yoko Fukuda, Masayuki Sano, Yoshio Kato, Yasuomi Takagi, Yoshiyuki Tanaka, Masaki Warashina, Tomoko Kuwabara, Shinya Y. Sawata, Yutaka Ikeda, Shun-ichi Kawahara, Kaul C. Sunil, Renu Wadhwa, and Kazunari Taira, Chemistry-based RNA technologies: demonstration of usefulness of libraries of ribozymes and short hairpin RNAs (shRNAs), Nucleic Acids Symposium Series 49, 91-92 (2005).

    田中好幸,天然のアロステリック様RNA酵素 -蛋白質不在の遺伝子発現フィードバック機構-,化学 59, 66-67 化学同人,京都 (2004).

    Hiroshi Yamaguchi, Shuji Oda, Yoshinori Kondo, Akira Ono and Yoshiyuki Tanaka, Spectroscopic analysis of DNA duplexes including T-T mismatches, Nucleic Acids Symposium Series 48, 113-114 (2004).

    田中好幸,ハンマーヘッド型リボザイム?金属イオン相互作用の分光学的解析,薬学雑誌 123, 305-313 (2003).

    桑原知子,藁科 雅岐,田中 好幸,多比良 和誠,センサー機能をもつ遺伝子治療薬 -核酸の熱力学的性質に基づくリボザイムの配列設計-,生物物理 40, 99-104 (2000). DOI: 10.2142/biophys.40.99

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